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Megace and Ejection fraction decreased - a phase IV clinical study of FDA data

Summary:

Ejection fraction decreased is reported as a side effect among people who take Megace (megestrol acetate), especially for people who are 60+ old, also take Lasix, and have Metastases to bone.

The phase IV clinical study analyzes which people have Ejection fraction decreased when taking Megace. It is created by eHealthMe based on reports of 9,969 people who have side effects when taking Megace from the FDA, and is updated regularly.

What is Megace?

Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.

What is Ejection fraction decreased?

Ejection fraction decreased (systolic heart failure) is found to be associated with 1,066 drugs and 1,252 conditions by eHealthMe. Check the latest studies of Ejection fraction decreased.

On Jul, 11, 2026

9,969 people reported to have side effects when taking Megace.
Among them, 58 people (0.58%) have Ejection fraction decreased.

Could Megace cause Ejection fraction decreased?

Among these 58 people:

What is the age of people who have Ejection fraction decreased when taking Megace? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.92 %
  • 40-49: 3.85 %
  • 50-59: 23.08 %
  • 60+: 71.15 %

What are other drugs people take besides Megace? *

  1. Aspirin: 20 people, 34.48%
  2. Lasix: 20 people, 34.48%
  3. Zometa: 19 people, 32.76%
  4. Tegretol: 18 people, 31.03%
  5. Digoxin: 17 people, 29.31%
  6. Lisinopril: 16 people, 27.59%
  7. Protonix: 16 people, 27.59%
  8. Avastin: 15 people, 25.86%
  9. Zoloft: 15 people, 25.86%
  10. Neurontin: 15 people, 25.86%

What are other side effects people have besides Ejection fraction decreased? *

  1. Cardiac Failure Congestive: 32 people, 55.17%
  2. Fall: 32 people, 55.17%
  3. Dyspnea (difficult or laboured breathing): 31 people, 53.45%
  4. Cardiomyopathy (weakening of the heart muscle): 30 people, 51.72%
  5. Pain: 30 people, 51.72%
  6. Fatigue (feeling of tiredness): 29 people, 50.00%
  7. Anaemia (lack of blood): 29 people, 50.00%
  8. Weakness: 29 people, 50.00%
  9. Pneumonia: 28 people, 48.28%
  10. Weight Decreased: 28 people, 48.28%

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 11 people, 18.97%
  2. Toothaches (tooth pain): 11 people, 18.97%
  3. Metastases To Bone (cancer spreads to bone): 11 people, 18.97%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 10 people, 17.24%
  5. High Blood Pressure: 9 people, 15.52%
  6. Pain: 8 people, 13.79%
  7. Breast Cancer: 8 people, 13.79%
  8. Constipation: 8 people, 13.79%
  9. Bone Pain: 7 people, 12.07%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 12.07%

* Approximation only. Some reports may have incomplete information.

Do you take Megace and have Ejection fraction decreased?

- Check whether Ejection fraction decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Megace:

Ejection fraction decreased treatments and more:

How severe was Ejection fraction decreased and when was it recovered:

Expand to all the drugs that have ingredients of megestrol acetate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Megace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ejection fraction decreased:

Browse all the conditions that are associated with Ejection fraction decreased:

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate (the active ingredients of Megace) and Megace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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