Phentermine and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Phentermine (phentermine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Singulair, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Joint swelling when taking Phentermine. It is created by eHealthMe based on reports of 15,359 people who have side effects when taking Phentermine from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Joint swelling?

Joint swelling is found to be associated with 2,121 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.

On Jul, 11, 2026

15,359 people reported to have side effects when taking Phentermine.
Among them, 48 people (0.31%) have Joint swelling.

Among these 48 people:

How long have people been on Phentermine when they have Joint swelling? *

What is the gender of people who have Joint swelling when taking Phentermine? *

female: 97.5 %
male: 2.5 %

What is the age of people who have Joint swelling when taking Phentermine? *

What are other drugs people take besides Phentermine? *

What are other side effects people have besides Joint swelling? *

Joint Pain: 20 people, 41.67%
Headache (pain in head): 14 people, 29.17%
Pain In Extremity: 13 people, 27.08%
Rashes (redness): 12 people, 25.00%
Peripheral Swelling: 10 people, 20.83%
High Blood Pressure: 9 people, 18.75%
Joint Stiffness: 8 people, 16.67%
Muscle Aches (muscle pain): 8 people, 16.67%
Gait Disturbance: 8 people, 16.67%
Nausea (feeling of having an urge to vomit): 8 people, 16.67%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.33%
Ovarian Cancer (cancer of ovary): 4 people, 8.33%
Weight Decreased: 3 people, 6.25%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 6.25%
High Blood Pressure: 3 people, 6.25%
Stress And Anxiety: 3 people, 6.25%
Depression: 2 people, 4.17%
Pneumonia: 2 people, 4.17%
Pain: 2 people, 4.17%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Phentermine and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phentermine:

Phentermine (19,870 reports)

Joint swelling treatments and more:

Joint swelling (143,797 reports)

Browse all side effects of Phentermine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Joint swelling (2,121 drugs)

Browse all the conditions that are associated with Joint swelling:

Joint swelling (2,934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride (the active ingredients of Phentermine) and Phentermine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.