Megestrol acetate and Cognitive disorder - a phase IV clinical study of FDA data

Summary:

Cognitive disorder is reported as a side effect among people who take Megestrol acetate (megestrol acetate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Oxycodone, and have Cancer pain.

The phase IV clinical study analyzes which people have Cognitive disorder when taking Megestrol acetate. It is created by eHealthMe based on reports of 5,359 people who have side effects when taking Megestrol acetate from the FDA, and is updated regularly.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

What is Cognitive disorder?

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving) is found to be associated with 1,653 drugs and 1,727 conditions by eHealthMe. Check the latest studies of Cognitive disorder.

On Jul, 18, 2026

5,359 people reported to have side effects when taking Megestrol acetate.
Among them, 18 people (0.34%) have Cognitive disorder.

Could Megestrol acetate cause Cognitive disorder?

Among these 18 people:

How long have people been on Megestrol acetate when they have Cognitive disorder? *

What is the gender of people who have Cognitive disorder when taking Megestrol acetate? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Cognitive disorder when taking Megestrol acetate? *

What are other drugs people take besides Megestrol acetate? *

What are other side effects people have besides Cognitive disorder? *

Dyspnea (difficult or laboured breathing): 12 people, 66.67%
Fatigue (feeling of tiredness): 11 people, 61.11%
Nausea And Vomiting: 10 people, 55.56%
Stress And Anxiety: 10 people, 55.56%
Depression: 9 people, 50.00%
Delirium (wild excitement): 9 people, 50.00%
Constipation: 9 people, 50.00%
Swallowing Difficulty: 8 people, 44.44%
Insomnia (sleeplessness): 8 people, 44.44%
Urinary Retention (the inability to completely or partially empty the bladder): 7 people, 38.89%

What are the existing conditions these people have? *

Cancer Pain: 7 people, 38.89%
Metastases To Bone (cancer spreads to bone): 6 people, 33.33%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 6 people, 33.33%
Breakthrough Pain: 5 people, 27.78%
Abdominal Pain: 2 people, 11.11%
Nausea (feeling of having an urge to vomit): 2 people, 11.11%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 11.11%
Allergic Rhinitis: 1 person, 5.56%
Back Pain: 1 person, 5.56%
Bone Marrow Disorder: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Megestrol acetate and have Cognitive disorder?

- Check whether Cognitive disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Megestrol acetate:

Megestrol acetate (5,427 reports)

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cognitive disorder:

Cognitive disorder (1,653 drugs)

Browse all the conditions that are associated with Cognitive disorder:

Cognitive disorder (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate (the active ingredients of Megestrol acetate) and Megestrol acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.