Megestrol acetate and Extremity contracture - a phase IV clinical study of FDA data

Summary:

Extremity contracture is reported as a side effect among people who take Megestrol acetate (megestrol acetate), especially for people who are female, 20-29 old, also take Magnevist, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Extremity contracture when taking Megestrol acetate. It is created by eHealthMe based on reports of 5,359 people who have side effects when taking Megestrol acetate from the FDA, and is updated regularly.

What is Megestrol acetate?

Megestrol acetate has active ingredients of megestrol acetate. It is often used in appetite - decreased. eHealthMe is studying from 5,427 Megestrol acetate users. Check the latest studies of Megestrol acetate.

What is Extremity contracture?

Extremity contracture (permanent shortening of a muscle or joint of arms and legs) is found to be associated with 206 drugs and 258 conditions by eHealthMe. Check the latest studies of Extremity contracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

5,359 people reported to have side effects when taking Megestrol acetate.
Among them, 11 people (0.21%) have Extremity contracture.

Could Megestrol acetate cause Extremity contracture?

Among these 11 people:

What is the gender of people who have Extremity contracture when taking Megestrol acetate? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Extremity contracture when taking Megestrol acetate? *

What are other drugs people take besides Megestrol acetate? *

What are other side effects people have besides Extremity contracture? *

Skin Disorder (skin disease): 9 people, 81.82%
Mobility Decreased (ability to move is reduced): 9 people, 81.82%
Pain: 9 people, 81.82%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 9 people, 81.82%
Peripheral Ischaemia (impaired circulation to an extremity): 7 people, 63.64%
Oedema (fluid collection in tissue): 7 people, 63.64%
Hyperkeratosis (thickening of the outer layer of the skin): 7 people, 63.64%
Skin Warm: 7 people, 63.64%
Skin Tightness: 7 people, 63.64%
Dry Skin: 7 people, 63.64%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 7 people, 63.64%
Nuclear Magnetic Resonance Imaging Abdominal: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Megestrol acetate and have Extremity contracture?

- Check whether Extremity contracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Megestrol acetate:

Megestrol acetate (5,427 reports)

Browse all side effects of Megestrol acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extremity contracture:

Extremity contracture (206 drugs)

Browse all the conditions that are associated with Extremity contracture:

Extremity contracture (258 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on megestrol acetate (the active ingredients of Megestrol acetate) and Megestrol acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.