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Melatonin and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Melatonin (melatonin), especially for people who are female, 60+ old, also take Megace, and have Pain.

The phase IV clinical study analyzes which people have Cachexia when taking Melatonin. It is created by eHealthMe based on reports of 53,570 people who have side effects when taking Melatonin from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,198 Melatonin users. Check the latest studies of Melatonin.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 737 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Oct, 10, 2025

53,570 people reported to have side effects when taking Melatonin.
Among them, 13 people (0.02%) have Cachexia.

Could Melatonin cause Cachexia?

Among these 13 people:

What is the gender of people who have Cachexia when taking Melatonin? *

  • female: 63.64 %
  • male: 36.36 %

What is the age of people who have Cachexia when taking Melatonin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 20 %
  • 60+: 80 %

What are other drugs people take besides Melatonin? *

  1. Amlodipine: 4 people, 30.77%
  2. Megace: 4 people, 30.77%
  3. Marinol: 3 people, 23.08%
  4. Prevacid: 3 people, 23.08%
  5. Celebrex: 3 people, 23.08%
  6. Mirabegron: 2 people, 15.38%
  7. Nitroglycerin: 2 people, 15.38%
  8. Nasonex: 2 people, 15.38%
  9. Nplate: 2 people, 15.38%
  10. Cipro: 2 people, 15.38%

What are other side effects people have besides Cachexia? *

  1. Weight Decreased: 5 people, 38.46%
  2. Fatigue (feeling of tiredness): 4 people, 30.77%
  3. Swallowing Difficulty: 3 people, 23.08%
  4. Anaemia (lack of blood): 3 people, 23.08%
  5. Cough: 3 people, 23.08%
  6. Fall: 3 people, 23.08%
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 3 people, 23.08%
  8. Respiratory Distress (difficulty in breathing): 3 people, 23.08%
  9. High Blood Pressure: 3 people, 23.08%
  10. Neoplasm Malignant (cancer tumour): 2 people, 15.38%

What are the existing conditions these people have? *

  1. Pain: 5 people, 38.46%
  2. High Blood Pressure: 4 people, 30.77%
  3. Stress And Anxiety: 4 people, 30.77%
  4. Parkinson's Disease: 4 people, 30.77%
  5. Depression: 3 people, 23.08%
  6. Agitation (state of anxiety or nervous excitement): 2 people, 15.38%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 15.38%
  8. Appetite Disorder (abnormal eating habits): 2 people, 15.38%
  9. Chickenpox (infection with varicella zoster virus): 2 people, 15.38%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melatonin:

Cachexia treatments and more:

How severe was Cachexia and when was it recovered:

Expand to all the drugs that have ingredients of melatonin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Browse all the conditions that are associated with Cachexia:

Drugs similar to Melatonin and Cachexia :

How the study uses the data?

The study uses data from the FDA. It is based on melatonin (the active ingredients of Melatonin) and Melatonin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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