Melatonin and Device expulsion - a phase IV clinical study of FDA data

Summary:

Device expulsion is reported as a side effect among people who take Melatonin (melatonin), especially for people who are female, 20-29 old, also take Paragard T 380A, and have Birth control.

The phase IV clinical study analyzes which people have Device expulsion when taking Melatonin. It is created by eHealthMe based on reports of 53,570 people who have side effects when taking Melatonin from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Device expulsion?

Device expulsion is found to be associated with 270 drugs and 502 conditions by eHealthMe. Check the latest studies of Device expulsion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

53,570 people reported to have side effects when taking Melatonin.
Among them, 28 people (0.05%) have Device expulsion.

Among these 28 people:

What is the gender of people who have Device expulsion when taking Melatonin? *

female: 68 %
male: 32 %

What is the age of people who have Device expulsion when taking Melatonin? *

What are other drugs people take besides Melatonin? *

What are other side effects people have besides Device expulsion? *

Diarrhea: 4 people, 14.29%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 10.71%
Nausea And Vomiting: 3 people, 10.71%
Pain: 3 people, 10.71%
Device Dislocation: 3 people, 10.71%
Dehydration (dryness resulting from the removal of water): 3 people, 10.71%
Drug Intolerance (drug sensitivity): 3 people, 10.71%
Hypotension (abnormally low blood pressure): 3 people, 10.71%
Heavy Or Prolong Menstrual Bleeding: 3 people, 10.71%
Heart Rate Increased: 3 people, 10.71%

What are the existing conditions these people have? *

Birth Control: 20 people, 71.43%
Stress And Anxiety: 3 people, 10.71%
Parkinson's Disease: 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%
Seasonal Allergy (allergic condition due to certain season): 2 people, 7.14%
Rickets (softening of bones): 2 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 7.14%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 3.57%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Melatonin and have Device expulsion?

- Check whether Device expulsion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Melatonin:

Melatonin (56,212 reports)

Device expulsion treatments and more:

Device expulsion (62,538 reports)

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Device expulsion:

Device expulsion (270 drugs)

Browse all the conditions that are associated with Device expulsion:

Device expulsion (502 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on melatonin (the active ingredients of Melatonin) and Melatonin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.