Memantine hydrochloride and Abnormal behavior - a phase IV clinical study of FDA data

Summary:

Abnormal behavior is reported as a side effect among people who take Memantine hydrochloride (memantine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Aricept, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Abnormal behavior when taking Memantine hydrochloride. It is created by eHealthMe based on reports of 3,046 people who have side effects when taking Memantine hydrochloride from the FDA, and is updated regularly.

What is Memantine hydrochloride?

Memantine hydrochloride has active ingredients of memantine hydrochloride. eHealthMe is studying from 3,076 Memantine hydrochloride users. Check the latest studies of Memantine hydrochloride.

What is Abnormal behavior?

Abnormal behavior is found to be associated with 1,360 drugs and 1,957 conditions by eHealthMe. Check the latest studies of Abnormal behavior.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

3,046 people reported to have side effects when taking Memantine hydrochloride.
Among them, 49 people (1.61%) have Abnormal behavior.

Could Memantine hydrochloride cause Abnormal behavior?

Among these 49 people:

How long have people been on Memantine hydrochloride when they have Abnormal behavior? *

What is the gender of people who have Abnormal behavior when taking Memantine hydrochloride? *

female: 63.83 %
male: 36.17 %

What is the age of people who have Abnormal behavior when taking Memantine hydrochloride? *

What are other drugs people take besides Memantine hydrochloride? *

Aricept: 10 people, 20.41%
Exelon: 7 people, 14.29%
Levemir: 6 people, 12.24%
Citalopram Hydrobromide: 6 people, 12.24%
Haldol: 6 people, 12.24%
Valium: 6 people, 12.24%
Atarax: 6 people, 12.24%
Levothyroxine Sodium: 5 people, 10.20%
Simvastatin: 5 people, 10.20%
Omeprazole: 5 people, 10.20%

What are other side effects people have besides Abnormal behavior? *

Agitation (state of anxiety or nervous excitement): 16 people, 32.65%
Dehydration (dryness resulting from the removal of water): 12 people, 24.49%
Confusional State: 12 people, 24.49%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 10 people, 20.41%
Drowsiness: 10 people, 20.41%
Disturbance In Attention: 8 people, 16.33%
High Blood Pressure: 8 people, 16.33%
Aggression: 7 people, 14.29%
Pneumonia: 6 people, 12.24%
Echolalia (meaningless repetition of another person's spoken words -psychiatric disorder): 6 people, 12.24%

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 16 people, 32.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 12.24%
Sleep Disorder: 5 people, 10.20%
Dementia (madness): 5 people, 10.20%
Depression: 4 people, 8.16%
Type 1 Diabetes: 3 people, 6.12%
Pneumonia: 3 people, 6.12%
Parkinson's Disease: 3 people, 6.12%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 6.12%
Delusion (a false belief or opinion): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Memantine hydrochloride and have Abnormal behavior?

- Check whether Abnormal behavior is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Memantine hydrochloride:

Memantine hydrochloride (3,076 reports)

Browse all side effects of Memantine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal behavior:

Abnormal behavior (1,360 drugs)

Browse all the conditions that are associated with Abnormal behavior:

Abnormal behavior (1,957 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on memantine hydrochloride (the active ingredients of Memantine hydrochloride) and Memantine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.