Memantine and Sepsis - a phase IV clinical study of FDA data

Summary:

Sepsis is reported as a side effect among people who take Memantine (memantine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Ondansetron, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Sepsis when taking Memantine. It is created by eHealthMe based on reports of 10,128 people who have side effects when taking Memantine from the FDA, and is updated regularly.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

What is Sepsis?

Sepsis (a severe blood infection that can lead to organ failure and death) is found to be associated with 2,522 drugs and 3,259 conditions by eHealthMe. Check the latest studies of Sepsis.



On Jul, 04, 2026

10,128 people reported to have side effects when taking Memantine.
Among them, 76 people (0.75%) have Sepsis.

Could Memantine cause Sepsis?

Among these 76 people:

How long have people been on Memantine when they have Sepsis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sepsis when taking Memantine? *

  • female: 35.62 %
  • male: 64.38 %

What is the age of people who have Sepsis when taking Memantine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.08 %
  • 40-49: 0.0 %
  • 50-59: 3.08 %
  • 60+: 93.85 %

What are other drugs people take besides Memantine? *

  1. Ondansetron: 10 people, 13.16%
  2. Eliquis: 8 people, 10.53%
  3. Metformin: 8 people, 10.53%
  4. Sertraline: 7 people, 9.21%
  5. Nuplazid: 7 people, 9.21%
  6. Pantoprazole: 7 people, 9.21%
  7. Folic Acid: 6 people, 7.89%
  8. Tamsulosin: 6 people, 7.89%
  9. Clopidogrel: 6 people, 7.89%
  10. Melatonin: 6 people, 7.89%

What are other side effects people have besides Sepsis? *

  1. Pneumonia: 16 people, 21.05%
  2. Urinary Tract Infection: 14 people, 18.42%
  3. Thrombocytopenia (decrease of platelets in blood): 10 people, 13.16%
  4. Weakness: 9 people, 11.84%
  5. Swallowing Difficulty: 8 people, 10.53%
  6. Death: 8 people, 10.53%
  7. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 8 people, 10.53%
  8. Delirium (wild excitement): 8 people, 10.53%
  9. Diarrhea: 8 people, 10.53%
  10. Hypotension (abnormally low blood pressure): 7 people, 9.21%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 12 people, 15.79%
  2. High Blood Pressure: 7 people, 9.21%
  3. Hallucinations (sensations that appear real but are created by your mind): 6 people, 7.89%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.58%
  5. Depression: 5 people, 6.58%
  6. High Blood Cholesterol: 5 people, 6.58%
  7. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 5 people, 6.58%
  8. Lung Cancer - Small Cell (lung cancer): 4 people, 5.26%
  9. Delusion (a false belief or opinion): 4 people, 5.26%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Memantine and have Sepsis?

- Check whether Sepsis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Memantine:

Sepsis treatments and more:

How severe was Sepsis and when was it recovered:

Expand to all the drugs that have ingredients of memantine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sepsis:

Browse all the conditions that are associated with Sepsis:


How the study uses the data?

The study uses data from the FDA. It is based on memantine (the active ingredients of Memantine) and Memantine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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