Menest and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Menest (estrogens, esterified), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Vioxx, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Stroke when taking Menest. It is created by eHealthMe based on reports of 815 people who have side effects when taking Menest from the FDA, and is updated regularly.

What is Menest?

Menest has active ingredients of estrogens, esterified. It is often used in hormone replacement therapy. eHealthMe is studying from 842 Menest users. Check the latest studies of Menest.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,391 drugs and 3,008 conditions by eHealthMe. Check the latest studies of Stroke.

On Sep, 20, 2025

815 people reported to have side effects when taking Menest.
Among them, 19 people (2.33%) have Stroke.

Among these 19 people:

How long have people been on Menest when they have Stroke? *

What is the gender of people who have Stroke when taking Menest? *

female: 100 %
male: 0.0 %

What is the age of people who have Stroke when taking Menest? *

What are other drugs people take besides Menest? *

What are other side effects people have besides Stroke? *

High Blood Pressure: 9 people, 47.37%
Stress And Anxiety: 9 people, 47.37%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 36.84%
High Blood Cholesterol: 6 people, 31.58%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 5 people, 26.32%
Depression: 4 people, 21.05%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 15.79%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.79%
Gastroenteritis (inflammation of stomach and intestine): 3 people, 15.79%
Hypertensive Crisis: 3 people, 15.79%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 36.84%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 26.32%
High Blood Pressure: 4 people, 21.05%
Bladder Spasm: 3 people, 15.79%
Diabetes: 3 people, 15.79%
Hypersensitivity: 3 people, 15.79%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 15.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
Osteoporosis (bones weak and more likely to break): 3 people, 15.79%
Migraine (headache): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Menest and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Menest:

Menest (842 reports)

Stroke treatments and more:

Stroke (334,630 reports)

Browse all side effects of Menest:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,391 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,008 conditions)

Drugs similar to Menest and Stroke :

How the study uses the data?

The study uses data from the FDA. It is based on estrogens, esterified (the active ingredients of Menest) and Menest (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.