Metaglip and Hypoglycemia - a phase IV clinical study of FDA data

Summary:

Hypoglycemia is reported as a side effect among people who take Metaglip (glipizide; metformin hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Aspirin, and have Diabetes.

The phase IV clinical study analyzes which people have Hypoglycemia when taking Metaglip. It is created by eHealthMe based on reports of 622 people who have side effects when taking Metaglip from the FDA, and is updated regularly.

What is Metaglip?

Metaglip has active ingredients of glipizide; metformin hydrochloride. It is often used in type 2 diabetes. eHealthMe is studying from 629 Metaglip users. Check the latest studies of Metaglip.

What is Hypoglycemia?

Hypoglycemia (low blood sugar) is found to be associated with 1,702 drugs and 2,379 conditions by eHealthMe. Check the latest studies of Hypoglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

622 people reported to have side effects when taking Metaglip.
Among them, 13 people (2.09%) have Hypoglycemia.

Among these 13 people:

How long have people been on Metaglip when they have Hypoglycemia? *

What is the gender of people who have Hypoglycemia when taking Metaglip? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Hypoglycemia when taking Metaglip? *

What are other drugs people take besides Metaglip? *

What are other side effects people have besides Hypoglycemia? *

Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 15.38%
Dyspnea (difficult or laboured breathing): 2 people, 15.38%
Drug Ineffective: 2 people, 15.38%
Renal Disorder (kidney disease): 1 person, 7.69%
Loss Of Consciousness: 1 person, 7.69%
Hypotension (abnormally low blood pressure): 1 person, 7.69%
Fatigue (feeling of tiredness): 1 person, 7.69%
Dizziness: 1 person, 7.69%
Diabetes: 1 person, 7.69%
Blood Glucose Increased: 1 person, 7.69%

What are the existing conditions these people have? *

Diabetes: 7 people, 53.85%
Urinary Tract Infection: 2 people, 15.38%
Type 1 Diabetes: 1 person, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Metaglip and have Hypoglycemia?

- Check whether Hypoglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metaglip:

Metaglip (629 reports)

Hypoglycemia treatments and more:

Hypoglycemia (57,734 reports)

How severe was Hypoglycemia and when was it recovered:

Hypoglycemia in Metaglip

Expand to all the drugs that have ingredients of glipizide; metformin hydrochloride:

Hypoglycemia and drugs with ingredients of glipizide; metformin hydrochloride (15 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metaglip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycemia:

Hypoglycemia (1,702 drugs)

Browse all the conditions that are associated with Hypoglycemia:

Hypoglycemia (2,379 conditions)

Related publications that referenced our studies

Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .
Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on glipizide; metformin hydrochloride (the active ingredients of Metaglip) and Metaglip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.