Metaxalone and Ddd - a phase IV clinical study of FDA data

Summary:

Ddd is reported as a side effect among people who take Metaxalone (metaxalone), especially for people who are female, 50-59 old, also take Zantac, and have Joint pain.

The phase IV clinical study analyzes which people have Ddd when taking Metaxalone. It is created by eHealthMe based on reports of 4,277 people who have side effects when taking Metaxalone from the FDA, and is updated regularly.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

What is Ddd?

Ddd is found to be associated with 1,322 drugs and 1,417 conditions by eHealthMe. Check the latest studies of Ddd.



On Jul, 09, 2026

4,277 people reported to have side effects when taking Metaxalone.
Among them, 19 people (0.44%) have Ddd.

Could Metaxalone cause Ddd?

Among these 19 people:

What is the gender of people who have Ddd when taking Metaxalone? *

  • female: 72.22 %
  • male: 27.78 %

What is the age of people who have Ddd when taking Metaxalone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.69 %
  • 30-39: 0.0 %
  • 40-49: 7.69 %
  • 50-59: 61.54 %
  • 60+: 23.08 %

What are other drugs people take besides Metaxalone? *

  1. Zantac: 7 people, 36.84%
  2. Celebrex: 6 people, 31.58%
  3. Ibuprofen: 5 people, 26.32%
  4. Ultram: 4 people, 21.05%
  5. Fentanyl: 4 people, 21.05%
  6. Aldactone: 4 people, 21.05%
  7. Fosamax: 4 people, 21.05%
  8. Naproxen: 4 people, 21.05%
  9. Botox: 4 people, 21.05%
  10. Soma: 4 people, 21.05%

What are other side effects people have besides Ddd? *

  1. Fall: 10 people, 52.63%
  2. Scoliosis (a medical condition in which a person's spine is curved from side to side): 9 people, 47.37%
  3. Intervertebral Disc Protrusion (spinal disc protrusion): 9 people, 47.37%
  4. Pain: 9 people, 47.37%
  5. Pain In Extremity: 8 people, 42.11%
  6. Gait Disturbance: 7 people, 36.84%
  7. Depression: 7 people, 36.84%
  8. Arthropathy: 6 people, 31.58%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 31.58%
  10. High Blood Pressure: 6 people, 31.58%

What are the existing conditions these people have? *

  1. Pain: 6 people, 31.58%
  2. Joint Pain: 6 people, 31.58%
  3. Haemorrhage (bleeding): 4 people, 21.05%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 21.05%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 21.05%
  6. Breakthrough Pain: 4 people, 21.05%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 21.05%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
  9. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 10.53%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Metaxalone and have Ddd?

- Check whether Ddd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metaxalone:

Ddd treatments and more:

  • Ddd (19,910 reports)

How severe was Ddd and when was it recovered:

Expand to all the drugs that have ingredients of metaxalone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metaxalone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ddd:

  • Ddd (1,322 drugs)

Browse all the conditions that are associated with Ddd:

  • Ddd (1,417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metaxalone (the active ingredients of Metaxalone) and Metaxalone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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