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Metformin hydrochloride and Acute myeloid leukaemia aggravated - a phase IV clinical study of FDA data

Summary:

Acute myeloid leukaemia aggravated is reported as a side effect among people who take Metformin hydrochloride (metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Omeprazole, and have High blood pressure.

The phase IV clinical study analyzes which people have Acute myeloid leukaemia aggravated when taking Metformin hydrochloride. It is created by eHealthMe based on reports of 54,785 people who have side effects when taking Metformin hydrochloride from the FDA, and is updated regularly.

What is Metformin hydrochloride?

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.

What is Acute myeloid leukaemia aggravated?

Acute myeloid leukaemia aggravated (serious acute cancer in which the bone marrow makes abnormal myeloblasts) is found to be associated with 691 drugs and 863 conditions by eHealthMe. Check the latest studies of Acute myeloid leukaemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

54,785 people reported to have side effects when taking Metformin hydrochloride.
Among them, 13 people (0.02%) have Acute myeloid leukaemia aggravated.

Could Metformin hydrochloride cause Acute myeloid leukaemia aggravated?

Among these 13 people:

How long have people been on Metformin hydrochloride when they have Acute myeloid leukaemia aggravated? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 33.33 %

What is the gender of people who have Acute myeloid leukaemia aggravated when taking Metformin hydrochloride? *

  • female: 30.77 %
  • male: 69.23 %

What is the age of people who have Acute myeloid leukaemia aggravated when taking Metformin hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 18.18 %
  • 50-59: 0.0 %
  • 60+: 81.82 %

What are other drugs people take besides Metformin hydrochloride? *

  1. Linagliptin: 3 people, 23.08%
  2. Omeprazole: 3 people, 23.08%
  3. Sitagliptin: 2 people, 15.38%
  4. Acyclovir: 2 people, 15.38%
  5. Aspirin: 2 people, 15.38%
  6. Azacitidine: 2 people, 15.38%
  7. Repaglinide: 2 people, 15.38%
  8. Revlimid: 2 people, 15.38%
  9. Simvastatin: 2 people, 15.38%
  10. Acetaminophen: 2 people, 15.38%

What are other side effects people have besides Acute myeloid leukaemia aggravated? *

  1. Febrile Neutropenia (fever with reduced white blood cells): 2 people, 15.38%
  2. Fever: 2 people, 15.38%
  3. Fatigue (feeling of tiredness): 1 person, 7.69%
  4. Bone Marrow Disorder: 1 person, 7.69%
  5. Cerebral Haemorrhage (bleeding within the brain): 1 person, 7.69%
  6. Confusional State: 1 person, 7.69%
  7. Constipation: 1 person, 7.69%
  8. Cough: 1 person, 7.69%
  9. Disease Progression: 1 person, 7.69%
  10. Dizziness: 1 person, 7.69%

What are the existing conditions these people have? *

  1. Constipation: 3 people, 23.08%
  2. High Blood Pressure: 3 people, 23.08%
  3. Dyslipidaemia (abnormal amount of lipids): 2 people, 15.38%
  4. Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 7.69%
  5. Tumor Associated Fever: 1 person, 7.69%
  6. Allergies: 1 person, 7.69%
  7. Anaemia Macrocytic (a macrocytic class of anaemia): 1 person, 7.69%
  8. Anorectal Abscess: 1 person, 7.69%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%
  10. Cardiac Failure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin hydrochloride and have Acute myeloid leukaemia aggravated?

- Check whether Acute myeloid leukaemia aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin hydrochloride:

Acute myeloid leukaemia aggravated treatments and more:

How severe was Acute myeloid leukaemia aggravated and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute myeloid leukaemia aggravated:

Browse all the conditions that are associated with Acute myeloid leukaemia aggravated:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin hydrochloride) and Metformin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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