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Metformin hydrochloride and Bundle branch block left - a phase IV clinical study of FDA data

Summary:

Bundle branch block left is reported as a side effect among people who take Metformin hydrochloride (metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Bundle branch block left when taking Metformin hydrochloride. It is created by eHealthMe based on reports of 54,785 people who have side effects when taking Metformin hydrochloride from the FDA, and is updated regularly.

What is Metformin hydrochloride?

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.

What is Bundle branch block left?

Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle) is found to be associated with 726 drugs and 794 conditions by eHealthMe. Check the latest studies of Bundle branch block left.

On Jul, 31, 2026

54,785 people reported to have side effects when taking Metformin hydrochloride.
Among them, 40 people (0.07%) have Bundle branch block left.

Could Metformin hydrochloride cause Bundle branch block left?

Among these 40 people:

How long have people been on Metformin hydrochloride when they have Bundle branch block left? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bundle branch block left when taking Metformin hydrochloride? *

  • female: 21.05 %
  • male: 78.95 %

What is the age of people who have Bundle branch block left when taking Metformin hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.71 %
  • 50-59: 25.71 %
  • 60+: 68.57 %

What are other drugs people take besides Metformin hydrochloride? *

  1. Aspirin: 19 people, 47.50%
  2. Pantoprazole: 14 people, 35.00%
  3. Ramipril: 13 people, 32.50%
  4. Hydrochlorothiazide: 12 people, 30.00%
  5. Carvedilol: 11 people, 27.50%
  6. Linagliptin: 11 people, 27.50%
  7. Telmisartan: 11 people, 27.50%
  8. Clopidogrel: 11 people, 27.50%
  9. Bisoprolol Fumarate: 8 people, 20.00%
  10. Amlodipine: 7 people, 17.50%

What are other side effects people have besides Bundle branch block left? *

  1. Ejection Fraction Decreased (systolic heart failure): 18 people, 45.00%
  2. Hypotension (abnormally low blood pressure): 18 people, 45.00%
  3. Weakness: 16 people, 40.00%
  4. Oedema Peripheral (superficial swelling): 16 people, 40.00%
  5. Cardiac Failure: 15 people, 37.50%
  6. Enlarged Heart: 15 people, 37.50%
  7. Fatigue (feeling of tiredness): 15 people, 37.50%
  8. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 15 people, 37.50%
  9. Left Ventricular Dysfunction: 15 people, 37.50%
  10. Electrocardiogram Qt Prolonged: 14 people, 35.00%

What are the existing conditions these people have? *

  1. High Blood Pressure: 13 people, 32.50%
  2. Cardiac Failure: 11 people, 27.50%
  3. Acute Kidney Failure: 11 people, 27.50%
  4. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 27.50%
  5. Carotid Arteriosclerosis (plaque deposition in artery): 10 people, 25.00%
  6. Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 7 people, 17.50%
  7. Multiple Myeloma (cancer of the plasma cells): 5 people, 12.50%
  8. Nausea (feeling of having an urge to vomit): 2 people, 5.00%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.00%
  10. Pain: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin hydrochloride and have Bundle branch block left?

- Check whether Bundle branch block left is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin hydrochloride:

Bundle branch block left treatments and more:

How severe was Bundle branch block left and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bundle branch block left:

Browse all the conditions that are associated with Bundle branch block left:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin hydrochloride) and Metformin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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