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Metformin hydrochloride and Colitis microscopic - a phase IV clinical study of FDA data

Summary:

Colitis microscopic is reported as a side effect among people who take Metformin hydrochloride (metformin hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Pregabalin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Colitis microscopic when taking Metformin hydrochloride. It is created by eHealthMe based on reports of 54,785 people who have side effects when taking Metformin hydrochloride from the FDA, and is updated regularly.

What is Metformin hydrochloride?

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.

What is Colitis microscopic?

Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps) is found to be associated with 377 drugs and 348 conditions by eHealthMe. Check the latest studies of Colitis microscopic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

54,785 people reported to have side effects when taking Metformin hydrochloride.
Among them, 41 people (0.07%) have Colitis microscopic.

Could Metformin hydrochloride cause Colitis microscopic?

Among these 41 people:

How long have people been on Metformin hydrochloride when they have Colitis microscopic? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 60 %
  • 10+ years: 0.0 %

What is the gender of people who have Colitis microscopic when taking Metformin hydrochloride? *

  • female: 95 %
  • male: 5 %

What is the age of people who have Colitis microscopic when taking Metformin hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 0.0 %
  • 60+: 87.5 %

What are other drugs people take besides Metformin hydrochloride? *

  1. Pregabalin: 29 people, 70.73%
  2. Arava: 27 people, 65.85%
  3. Sulfasalazine: 27 people, 65.85%
  4. Desoximetasone: 27 people, 65.85%
  5. Acetaminophen: 26 people, 63.41%
  6. Ergocalciferol: 26 people, 63.41%
  7. Mycophenolate Mofetil: 26 people, 63.41%
  8. Methotrexate: 26 people, 63.41%
  9. Prednisone: 26 people, 63.41%
  10. Humira: 26 people, 63.41%

What are other side effects people have besides Colitis microscopic? *

  1. Diarrhea: 30 people, 73.17%
  2. Joint Swelling: 27 people, 65.85%
  3. Peripheral Swelling: 27 people, 65.85%
  4. Insomnia (sleeplessness): 27 people, 65.85%
  5. Joint Pain: 27 people, 65.85%
  6. Herpes Zoster: 27 people, 65.85%
  7. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 27 people, 65.85%
  8. Glaucoma (increased fluid pressure in the eye with vision loss): 27 people, 65.85%
  9. Mobility Decreased (ability to move is reduced): 27 people, 65.85%
  10. Multiple Allergies (allergy to multiple agents): 27 people, 65.85%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 27 people, 65.85%
  2. High Blood Cholesterol: 21 people, 51.22%
  3. High Blood Pressure: 19 people, 46.34%
  4. Colitis (inflammation of colon): 3 people, 7.32%
  5. Weight Loss: 2 people, 4.88%
  6. Urinary Tract Infection: 2 people, 4.88%
  7. Synovitis (inflammation of the synovial membrane): 2 people, 4.88%
  8. Sinusitis (inflammation of sinus): 2 people, 4.88%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.88%
  10. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin hydrochloride and have Colitis microscopic?

- Check whether Colitis microscopic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin hydrochloride:

Colitis microscopic treatments and more:

How severe was Colitis microscopic and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Colitis microscopic:

Browse all the conditions that are associated with Colitis microscopic:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin hydrochloride) and Metformin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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