Metformin hydrochloride and Thyroid cyst - a phase IV clinical study of FDA data

Summary:

Thyroid cyst is reported as a side effect among people who take Metformin hydrochloride (metformin hydrochloride), especially for people who are male, 60+ old, also take Dilaudid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Thyroid cyst when taking Metformin hydrochloride. It is created by eHealthMe based on reports of 54,785 people who have side effects when taking Metformin hydrochloride from the FDA, and is updated regularly.

What is Metformin hydrochloride?

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 58,646 Metformin hydrochloride users. Check the latest studies of Metformin hydrochloride.

What is Thyroid cyst?

Thyroid cyst is found to be associated with 235 drugs and 282 conditions by eHealthMe. Check the latest studies of Thyroid cyst.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

54,785 people reported to have side effects when taking Metformin hydrochloride.
Among them, 15 people (0.03%) have Thyroid cyst.

Could Metformin hydrochloride cause Thyroid cyst?

Among these 15 people:

What is the gender of people who have Thyroid cyst when taking Metformin hydrochloride? *

female: 40 %
male: 60 %

What is the age of people who have Thyroid cyst when taking Metformin hydrochloride? *

What are other drugs people take besides Metformin hydrochloride? *

What are other side effects people have besides Thyroid cyst? *

Dyspnea (difficult or laboured breathing): 10 people, 66.67%
Fatigue (feeling of tiredness): 10 people, 66.67%
Osteomyelitis (infection of bone): 9 people, 60.00%
Osteonecrosis Of Jaw (death of bone of jaw): 8 people, 53.33%
Tooth Fracture: 8 people, 53.33%
Pain: 8 people, 53.33%
Back Pain: 8 people, 53.33%
Sinusitis (inflammation of sinus): 8 people, 53.33%
Bone Pain: 8 people, 53.33%
Infection: 7 people, 46.67%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 33.33%
Primary Immunodeficiency Syndrome: 4 people, 26.67%
Immunodeficiency Common Variable: 4 people, 26.67%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Metastases To Bone (cancer spreads to bone): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin hydrochloride and have Thyroid cyst?

- Check whether Thyroid cyst is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin hydrochloride:

Metformin hydrochloride (58,646 reports)

Thyroid cyst treatments and more:

Thyroid cyst (1,005 reports)

Browse all side effects of Metformin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid cyst:

Thyroid cyst (235 drugs)

Browse all the conditions that are associated with Thyroid cyst:

Thyroid cyst (282 conditions)

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin hydrochloride) and Metformin hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.