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Metformin and Amniotic cavity infection - a phase IV clinical study of FDA data

Summary:

Amniotic cavity infection is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are 30-39 old, have been taking the drug for 1 - 6 months also take Makena, and have Premature delivery.

The phase IV clinical study analyzes which people have Amniotic cavity infection when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Amniotic cavity infection?

Amniotic cavity infection is found to be associated with 67 drugs and 182 conditions by eHealthMe. Check the latest studies of Amniotic cavity infection.

On Jul, 12, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 29 people (0.01%) have Amniotic cavity infection.

Could Metformin cause Amniotic cavity infection?

Among these 29 people:

How long have people been on Metformin when they have Amniotic cavity infection? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Amniotic cavity infection when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 88 %
  • 40-49: 8 %
  • 50-59: 0.0 %
  • 60+: 4 %

What are other drugs people take besides Metformin? *

  1. Makena: 7 people, 24.14%
  2. Rosiglitazone: 4 people, 13.79%
  3. Insulin: 4 people, 13.79%
  4. Monopril: 4 people, 13.79%
  5. Aspirin: 4 people, 13.79%
  6. Nitrofurantoin: 3 people, 10.34%
  7. Azithromycin: 2 people, 6.90%
  8. Cefazolin: 2 people, 6.90%
  9. Metoprolol Tartrate: 2 people, 6.90%
  10. Erythromycin: 2 people, 6.90%

What are other side effects people have besides Amniotic cavity infection? *

  1. Premature Rupture Of Membranes: 12 people, 41.38%
  2. Premature Delivery: 12 people, 41.38%
  3. Maternal Exposure During Pregnancy (use of substance during pregnancy): 11 people, 37.93%
  4. Birth Control: 8 people, 27.59%
  5. Cervical Incompetence (serious pregnancy complication in which the cervix starts to open): 8 people, 27.59%
  6. Gestational Diabetes (diabetes in pregnancy): 6 people, 20.69%
  7. Abortion Spontaneous (naturally occurring miscarriage): 6 people, 20.69%
  8. Pre-Eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman): 5 people, 17.24%
  9. Live Birth: 4 people, 13.79%
  10. Urinary Tract Infection: 4 people, 13.79%

What are the existing conditions these people have? *

  1. Premature Delivery: 7 people, 24.14%
  2. Gestational Diabetes (diabetes in pregnancy): 6 people, 20.69%
  3. Urinary Tract Infection: 4 people, 13.79%
  4. High Blood Pressure: 4 people, 13.79%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.90%
  6. Insulin Resistance: 1 person, 3.45%
  7. Indigestion: 1 person, 3.45%
  8. Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 1 person, 3.45%
  9. Depression: 1 person, 3.45%
  10. Birth Control: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Amniotic cavity infection?

- Check whether Amniotic cavity infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Amniotic cavity infection treatments and more:

How severe was Amniotic cavity infection and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Amniotic cavity infection:

Browse all the conditions that are associated with Amniotic cavity infection:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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