Metformin and Bartholin's cyst - a phase IV clinical study of FDA data

Summary:

Bartholin's cyst is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are 40-49 old, also take Zometa, and have Inflammatory bowel disease.

The phase IV clinical study analyzes which people have Bartholin's cyst when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,358 Metformin users. Check the latest studies of Metformin.

What is Bartholin's cyst?

Bartholin's cyst (cyst is formed on one or both of the two bartholin's glands, which are located one on either side of the opening of the vagina) is found to be associated with 87 drugs and 133 conditions by eHealthMe. Check the latest studies of Bartholin's cyst.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 16 people (0.0%) have Bartholin's cyst.

Could Metformin cause Bartholin's cyst?

Among these 16 people:

What is the age of people who have Bartholin's cyst when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 84.62 %
  • 50-59: 7.69 %
  • 60+: 0.0 %

What are other drugs people take besides Metformin? *

  1. Zometa: 13 people, 81.25%
  2. Vicodin: 12 people, 75.00%
  3. Oxycontin: 12 people, 75.00%
  4. Celexa: 12 people, 75.00%
  5. Revlimid: 8 people, 50.00%
  6. Omeprazole: 8 people, 50.00%
  7. Flomax: 6 people, 37.50%
  8. Effexor: 6 people, 37.50%
  9. Hydrochlorothiazide: 2 people, 12.50%
  10. Calcium: 1 person, 6.25%

What are other side effects people have besides Bartholin's cyst? *

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 81.25%
  2. Pleural Effusion (water on the lungs): 13 people, 81.25%
  3. Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 81.25%
  4. Iron Deficiency Anaemia: 13 people, 81.25%
  5. Stress And Anxiety: 13 people, 81.25%
  6. Emotional Distress: 13 people, 81.25%
  7. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 13 people, 81.25%
  8. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 13 people, 81.25%
  9. Pain: 13 people, 81.25%
  10. High Blood Pressure: 12 people, 75.00%

What are the existing conditions these people have? *

  1. Inflammatory Bowel Disease: 2 people, 12.50%
  2. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 6.25%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  4. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 6.25%
  5. Pain: 1 person, 6.25%
  6. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Bartholin's cyst?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Bartholin's cyst treatments and more:

How severe was Bartholin's cyst and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bartholin's cyst:

Browse all the conditions that are associated with Bartholin's cyst:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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