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Metformin and Chalazion - a phase IV clinical study of FDA data

Summary:

Chalazion is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are female, 50-59 old, also take Neurontin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Chalazion when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.

What is Chalazion?

Chalazion (cyst in the eyelid) is found to be associated with 89 drugs and 248 conditions by eHealthMe. Check the latest studies of Chalazion.

On Aug, 08, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 12 people (0.0%) have Chalazion.

Could Metformin cause Chalazion?

Among these 12 people:

What is the gender of people who have Chalazion when taking Metformin? *

  • female: 58.33 %
  • male: 41.67 %

What is the age of people who have Chalazion when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 44.44 %
  • 60+: 33.33 %

What are other drugs people take besides Metformin? *

  1. Clonazepam: 3 people, 25.00%
  2. Mayzent: 3 people, 25.00%
  3. Alprazolam: 3 people, 25.00%
  4. Glyxambi: 3 people, 25.00%
  5. Nystop: 3 people, 25.00%
  6. Ampyra: 3 people, 25.00%
  7. Hydrochlorothiazide: 3 people, 25.00%
  8. Hydrocodone Bitartrate And Acetaminophen: 3 people, 25.00%
  9. Pantoprazole: 3 people, 25.00%
  10. Neurontin: 3 people, 25.00%

What are other side effects people have besides Chalazion? *

  1. Hordeolum (small collection of pus (abscess) on the eyelid): 4 people, 33.33%
  2. High Blood Pressure: 3 people, 25.00%
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 3 people, 25.00%
  4. Urinary Tract Infection: 3 people, 25.00%
  5. Fall: 3 people, 25.00%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 25.00%
  7. Hepatomegaly (abnormal enlargement of the liver): 2 people, 16.67%
  8. Gait Disturbance: 2 people, 16.67%
  9. Eye Pain: 2 people, 16.67%
  10. Eyelid Tumor: 2 people, 16.67%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
  2. Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
  3. Sleep Disorder: 1 person, 8.33%
  4. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 8.33%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
  6. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 8.33%
  7. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
  8. Dyslipidaemia (abnormal amount of lipids): 1 person, 8.33%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Chalazion?

- Check whether Chalazion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Chalazion treatments and more:

How severe was Chalazion and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chalazion:

Browse all the conditions that are associated with Chalazion:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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