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Metformin and Gingival abscess - a phase IV clinical study of FDA data

Summary:

Gingival abscess is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are female, 50-59 old, also take Sandostatin, and have Vipoma.

The phase IV clinical study analyzes which people have Gingival abscess when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,358 Metformin users. Check the latest studies of Metformin.

What is Gingival abscess?

Gingival abscess (pus in gums) is found to be associated with 217 drugs and 209 conditions by eHealthMe. Check the latest studies of Gingival abscess.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 49 people (0.01%) have Gingival abscess.

Could Metformin cause Gingival abscess?

Among these 49 people:

What is the gender of people who have Gingival abscess when taking Metformin? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Gingival abscess when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.44 %
  • 40-49: 0.0 %
  • 50-59: 63.41 %
  • 60+: 34.15 %

What are other drugs people take besides Metformin? *

  1. Januvia: 29 people, 59.18%
  2. Sandostatin: 29 people, 59.18%
  3. Pantoprazole: 18 people, 36.73%
  4. Acetaminophen: 17 people, 34.69%
  5. Dexamethasone: 12 people, 24.49%
  6. Pantoprazole Sodium: 12 people, 24.49%
  7. Naproxen: 11 people, 22.45%
  8. Ondansetron: 11 people, 22.45%
  9. Repaglinide: 11 people, 22.45%
  10. Penicillin V Potassium: 11 people, 22.45%

What are other side effects people have besides Gingival abscess? *

  1. Blood Glucose Increased: 33 people, 67.35%
  2. Fatigue (feeling of tiredness): 33 people, 67.35%
  3. Stress And Anxiety: 32 people, 65.31%
  4. Abdominal Pain: 31 people, 63.27%
  5. Constipation: 31 people, 63.27%
  6. High Blood Pressure: 31 people, 63.27%
  7. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 31 people, 63.27%
  8. Pain In Extremity: 31 people, 63.27%
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 31 people, 63.27%
  10. Injection Site Pain: 30 people, 61.22%

What are the existing conditions these people have? *

  1. Vipoma (endocrine tumour): 24 people, 48.98%
  2. Psoriasis (immune-mediated disease that affects the skin): 4 people, 8.16%
  3. High Blood Pressure: 4 people, 8.16%
  4. Immunodeficiency Common Variable: 4 people, 8.16%
  5. Osteoporosis (bones weak and more likely to break): 3 people, 6.12%
  6. Cardiac Disorder: 2 people, 4.08%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.08%
  8. Pain: 2 people, 4.08%
  9. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 4.08%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Gingival abscess?

- Check whether Gingival abscess is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Gingival abscess treatments and more:

How severe was Gingival abscess and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival abscess:

Browse all the conditions that are associated with Gingival abscess:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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