Metformin and Panic attacks - a phase IV clinical study of FDA data

Summary:

Panic attacks is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Clonazepam, and have High blood pressure.

The phase IV clinical study analyzes which people have Panic attacks when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,278 Metformin users. Check the latest studies of Metformin.

What is Panic attacks?

Panic attacks is found to be associated with 2,606 drugs and 2,065 conditions by eHealthMe. Check the latest studies of Panic attacks.



On Sep, 09, 2025

453,860 people reported to have side effects when taking Metformin.
Among them, 1,025 people (0.23%) have Panic attacks.

Could Metformin cause Panic attacks?

Among these 1,025 people:

How long have people been on Metformin when they have Panic attacks? *

  • < 1 month: 32.43 %
  • 1 - 6 months: 29.73 %
  • 6 - 12 months: 2.7 %
  • 1 - 2 years: 21.62 %
  • 2 - 5 years: 13.51 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Panic attacks when taking Metformin? *

  • female: 72.4 %
  • male: 27.6 %

What is the age of people who have Panic attacks when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.13 %
  • 10-19: 1.29 %
  • 20-29: 2.96 %
  • 30-39: 8.51 %
  • 40-49: 17.78 %
  • 50-59: 29.38 %
  • 60+: 39.95 %

What are other drugs people take besides Metformin? *

  1. Clonazepam: 139 people, 13.56%
  2. Simvastatin: 135 people, 13.17%
  3. Prednisone: 125 people, 12.20%
  4. Lasix: 105 people, 10.24%
  5. Aspirin: 102 people, 9.95%
  6. Lisinopril: 95 people, 9.27%
  7. Klonopin: 94 people, 9.17%
  8. Prilosec: 88 people, 8.59%
  9. Ventolin: 87 people, 8.49%
  10. Chantix: 87 people, 8.49%

What are other side effects people have besides Panic attacks? *

  1. Stress And Anxiety: 427 people, 41.66%
  2. Dyspnea (difficult or laboured breathing): 295 people, 28.78%
  3. Pain: 275 people, 26.83%
  4. High Blood Pressure: 263 people, 25.66%
  5. Back Pain: 252 people, 24.59%
  6. Depression: 250 people, 24.39%
  7. Diarrhea: 229 people, 22.34%
  8. Fatigue (feeling of tiredness): 224 people, 21.85%
  9. Weakness: 212 people, 20.68%
  10. Nausea (feeling of having an urge to vomit): 211 people, 20.59%

What are the existing conditions these people have? *

  1. High Blood Pressure: 158 people, 15.41%
  2. Asthma: 136 people, 13.27%
  3. High Blood Cholesterol: 136 people, 13.27%
  4. Depression: 117 people, 11.41%
  5. Pain: 108 people, 10.54%
  6. Stress And Anxiety: 103 people, 10.05%
  7. Quit Smoking: 58 people, 5.66%
  8. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 51 people, 4.98%
  9. Bipolar Disorder (mood disorder): 46 people, 4.49%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 44 people, 4.29%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Panic attacks?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Panic attacks treatments and more:

How severe was Panic attacks and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Metformin side effects:

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Panic attacks:

Browse all the drugs that are associated with Panic attacks:

Common conditions associated with Panic attacks:

Browse all the conditions that are associated with Panic attacks:

Drugs similar to Metformin and Panic attacks :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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