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Metformin and Postoperative adhesion - a phase IV clinical study of FDA data

Summary:

Postoperative adhesion is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are male, 60+ old, also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Postoperative adhesion when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Postoperative adhesion?

Postoperative adhesion is found to be associated with 130 drugs and 198 conditions by eHealthMe. Check the latest studies of Postoperative adhesion.

On Jul, 29, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 11 people (0.0%) have Postoperative adhesion.

Could Metformin cause Postoperative adhesion?

Among these 11 people:

What is the gender of people who have Postoperative adhesion when taking Metformin? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Postoperative adhesion when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 14.29 %
  • 60+: 85.71 %

What are other drugs people take besides Metformin? *

  1. Singulair: 3 people, 27.27%
  2. Lyrica: 3 people, 27.27%
  3. Humira: 3 people, 27.27%
  4. Zopiclone: 2 people, 18.18%
  5. Magnesium: 2 people, 18.18%
  6. Flomax: 2 people, 18.18%
  7. Dilaudid: 2 people, 18.18%
  8. Zofran: 2 people, 18.18%
  9. Nitrolingual: 2 people, 18.18%
  10. Colace: 2 people, 18.18%

What are other side effects people have besides Postoperative adhesion? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 45.45%
  2. Indigestion: 5 people, 45.45%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 45.45%
  4. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 5 people, 45.45%
  5. Abdominal Pain: 4 people, 36.36%
  6. Gastritis (inflammation of stomach): 4 people, 36.36%
  7. High Blood Pressure: 4 people, 36.36%
  8. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 4 people, 36.36%
  9. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 36.36%
  10. Nausea And Vomiting: 4 people, 36.36%

What are the existing conditions these people have? *

  1. Gout (uric acid crystals building up in the body): 2 people, 18.18%
  2. B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 2 people, 18.18%
  3. Pancreatic Carcinoma (pancreatic cancer): 2 people, 18.18%
  4. Blood Pressure Abnormal: 2 people, 18.18%
  5. Neuroendocrine Tumor: 2 people, 18.18%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 18.18%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  9. Blood Glucose Increased: 1 person, 9.09%
  10. Bone Sarcoma (bone cancer): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Postoperative adhesion?

- Check whether Postoperative adhesion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Postoperative adhesion treatments and more:

How severe was Postoperative adhesion and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Postoperative adhesion:

Browse all the conditions that are associated with Postoperative adhesion:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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