Metformin and Procedural hypotension - a phase IV clinical study of FDA data

Summary:

Procedural hypotension is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are female, 60+ old, also take Multivitamin, and have Ill-defined disorder.

The phase IV clinical study analyzes which people have Procedural hypotension when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.

What is Procedural hypotension?

Procedural hypotension is found to be associated with 151 drugs and 354 conditions by eHealthMe. Check the latest studies of Procedural hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 19 people (0.0%) have Procedural hypotension.

Could Metformin cause Procedural hypotension?

Among these 19 people:

What is the gender of people who have Procedural hypotension when taking Metformin? *

female: 60 %
male: 40 %

What is the age of people who have Procedural hypotension when taking Metformin? *

What are other drugs people take besides Metformin? *

What are other side effects people have besides Procedural hypotension? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 26.32%
Dyspnea (difficult or laboured breathing): 5 people, 26.32%
Thrombocytopenia (decrease of platelets in blood): 5 people, 26.32%
Acute Kidney Failure: 4 people, 21.05%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 21.05%
Blood Creatine Increased: 4 people, 21.05%
Weakness: 4 people, 21.05%
Right Ventricular Failure (right half of the heart fails to work): 4 people, 21.05%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 21.05%
Arrhythmias (irregular heartbeat): 4 people, 21.05%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 21.05%
Ill-Defined Disorder: 4 people, 21.05%
High Blood Pressure: 3 people, 15.79%
Oedema Peripheral (superficial swelling): 2 people, 10.53%
Suicide Attempt: 1 person, 5.26%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 1 person, 5.26%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
Mucosal Inflammation (infection of mucous membrane): 1 person, 5.26%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Procedural hypotension?

- Check whether Procedural hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Metformin (465,355 reports)

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Procedural hypotension:

Procedural hypotension (151 drugs)

Browse all the conditions that are associated with Procedural hypotension:

Procedural hypotension (354 conditions)

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.