Methadose and Diarrhea - a phase IV clinical study of FDA data

Summary:

Diarrhea is reported as a side effect among people who take Methadose (methadone hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cymbalta, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Diarrhea when taking Methadose. It is created by eHealthMe based on reports of 4,441 people who have side effects when taking Methadose from the FDA, and is updated regularly.

What is Methadose?

Methadose has active ingredients of methadone hydrochloride. It is often used in pain. eHealthMe is studying from 5,101 Methadose users. Check the latest studies of Methadose.

What is Diarrhea?

Diarrhea is found to be associated with 3,732 drugs and 5,750 conditions by eHealthMe. Check the latest studies of Diarrhea.

On Jul, 07, 2026

4,441 people reported to have side effects when taking Methadose.
Among them, 49 people (1.1%) have Diarrhea.

Among these 49 people:

How long have people been on Methadose when they have Diarrhea? *

What is the gender of people who have Diarrhea when taking Methadose? *

female: 65.91 %
male: 34.09 %

What is the age of people who have Diarrhea when taking Methadose? *

What are other drugs people take besides Methadose? *

What are other side effects people have besides Diarrhea? *

Nausea (feeling of having an urge to vomit): 24 people, 48.98%
Nausea And Vomiting: 20 people, 40.82%
Dyspnea (difficult or laboured breathing): 17 people, 34.69%
Headache (pain in head): 16 people, 32.65%
Mood Swings (an extreme or rapid change in mood): 11 people, 22.45%
Agitation (state of anxiety or nervous excitement): 11 people, 22.45%
Chest Pain: 11 people, 22.45%
Suicidal Ideation: 11 people, 22.45%
Fatigue (feeling of tiredness): 11 people, 22.45%
Skin Blushing/flushing (a sudden reddening of the face, neck): 10 people, 20.41%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 16.33%
Drug Dependence: 4 people, 8.16%
Colon Cancer: 3 people, 6.12%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.12%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.12%
Stress And Anxiety: 2 people, 4.08%
High Blood Cholesterol: 2 people, 4.08%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 4.08%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 4.08%
Depression: 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Methadose and have Diarrhea?

- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methadose:

Methadose (5,101 reports)

Diarrhea treatments and more:

Diarrhea (756,290 reports)

Browse all side effects of Methadose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea:

Diarrhea (3,732 drugs)

Browse all the conditions that are associated with Diarrhea:

Diarrhea (5,750 conditions)

Related publications that referenced our studies

McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on methadone hydrochloride (the active ingredients of Methadose) and Methadose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.