Methocarbamol and Drug intolerance - a phase IV clinical study of FDA data

Summary:

Drug intolerance is reported as a side effect among people who take Methocarbamol (methocarbamol), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lyrica, and have Narcolepsy.

The phase IV clinical study analyzes which people have Drug intolerance when taking Methocarbamol. It is created by eHealthMe based on reports of 16,788 people who have side effects when taking Methocarbamol from the FDA, and is updated regularly.

What is Methocarbamol?

Methocarbamol has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 17,766 Methocarbamol users. Check the latest studies of Methocarbamol.

What is Drug intolerance?

Drug intolerance (drug sensitivity) is found to be associated with 1,907 drugs and 1,599 conditions by eHealthMe. Check the latest studies of Drug intolerance.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

16,788 people reported to have side effects when taking Methocarbamol.
Among them, 75 people (0.45%) have Drug intolerance.

Could Methocarbamol cause Drug intolerance?

Among these 75 people:

How long have people been on Methocarbamol when they have Drug intolerance? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 83.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Drug intolerance when taking Methocarbamol? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Drug intolerance when taking Methocarbamol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.98 %
  • 30-39: 4.65 %
  • 40-49: 11.63 %
  • 50-59: 34.88 %
  • 60+: 41.86 %

What are other drugs people take besides Methocarbamol? *

  1. Lyrica: 16 people, 21.33%
  2. Zofran: 12 people, 16.00%
  3. Vitamin D3: 12 people, 16.00%
  4. Singulair: 12 people, 16.00%
  5. Neurontin: 10 people, 13.33%
  6. Xyrem: 10 people, 13.33%
  7. Robaxin: 10 people, 13.33%
  8. Gabapentin: 10 people, 13.33%
  9. Klonopin: 10 people, 13.33%
  10. Acetaminophen: 9 people, 12.00%

What are other side effects people have besides Drug intolerance? *

  1. Nausea (feeling of having an urge to vomit): 26 people, 34.67%
  2. Malaise (a feeling of general discomfort or uneasiness): 19 people, 25.33%
  3. Joint Pain: 16 people, 21.33%
  4. Fatigue (feeling of tiredness): 16 people, 21.33%
  5. Headache (pain in head): 15 people, 20.00%
  6. Back Pain: 15 people, 20.00%
  7. Urinary Tract Infection: 14 people, 18.67%
  8. Fever: 13 people, 17.33%
  9. Constipation: 13 people, 17.33%
  10. Weight Decreased: 13 people, 17.33%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 13.33%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.67%
  3. Multiple Myeloma (cancer of the plasma cells): 8 people, 10.67%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.33%
  5. Nausea (feeling of having an urge to vomit): 7 people, 9.33%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 8.00%
  7. Depression: 5 people, 6.67%
  8. Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 5 people, 6.67%
  9. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.33%
  10. High Blood Pressure: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

Do you take Methocarbamol and have Drug intolerance?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methocarbamol:

Drug intolerance treatments and more:

How severe was Drug intolerance and when was it recovered:

Expand to all the drugs that have ingredients of methocarbamol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methocarbamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug intolerance:

Browse all the conditions that are associated with Drug intolerance:


How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol (the active ingredients of Methocarbamol) and Methocarbamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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