Methotrexate and Computerised tomogram abnormal - a phase IV clinical study of FDA data

Summary:

Computerised tomogram abnormal is reported as a side effect among people who take Methotrexate (methotrexate sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Folic Acid, and have Histiocytosis haematophagic.

The phase IV clinical study analyzes which people have Computerised tomogram abnormal when taking Methotrexate. It is created by eHealthMe based on reports of 599,650 people who have side effects when taking Methotrexate from the FDA, and is updated regularly.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,298 Methotrexate users. Check the latest studies of Methotrexate.

What is Computerised tomogram abnormal?

Computerised tomogram abnormal is found to be associated with 699 drugs and 648 conditions by eHealthMe. Check the latest studies of Computerised tomogram abnormal.

On Oct, 28, 2025

599,650 people reported to have side effects when taking Methotrexate.
Among them, 222 people (0.04%) have Computerised tomogram abnormal.

Could Methotrexate cause Computerised tomogram abnormal?

Among these 222 people:

How long have people been on Methotrexate when they have Computerised tomogram abnormal? *

What is the gender of people who have Computerised tomogram abnormal when taking Methotrexate? *

female: 57.67 %
male: 42.33 %

What is the age of people who have Computerised tomogram abnormal when taking Methotrexate? *

What are other drugs people take besides Methotrexate? *

What are other side effects people have besides Computerised tomogram abnormal? *

Fever: 48 people, 21.62%
Dyspnea (difficult or laboured breathing): 29 people, 13.06%
Headache (pain in head): 28 people, 12.61%
Nausea (feeling of having an urge to vomit): 27 people, 12.16%
Hypotension (abnormally low blood pressure): 26 people, 11.71%
Fatigue (feeling of tiredness): 25 people, 11.26%
Joint Pain: 24 people, 10.81%
Thrombocytopenia (decrease of platelets in blood): 22 people, 9.91%
Cough: 21 people, 9.46%
Confusion: 21 people, 9.46%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 11 people, 4.95%
Histiocytosis Haematophagic: 11 people, 4.95%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 10 people, 4.50%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 6 people, 2.70%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 2.70%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 2.70%
Metastases To Bone (cancer spreads to bone): 6 people, 2.70%
Infection: 5 people, 2.25%
Osteoporosis (bones weak and more likely to break): 5 people, 2.25%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 1.80%

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate and have Computerised tomogram abnormal?

- Check whether Computerised tomogram abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methotrexate:

Methotrexate (604,298 reports)

Common Methotrexate side effects:

Browse all side effects of Methotrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Computerised tomogram abnormal:

Browse all the drugs that are associated with Computerised tomogram abnormal:

Computerised tomogram abnormal (699 drugs)

Common conditions associated with Computerised tomogram abnormal:

Browse all the conditions that are associated with Computerised tomogram abnormal:

Computerised tomogram abnormal (648 conditions)

Drugs similar to Methotrexate and Computerised tomogram abnormal :

Related publications that referenced our studies

Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate) and Methotrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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