Methotrexate and Fatigue - from FDA reports
Fatigue is found among people who take Methotrexate, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Psoriatic arthropathy. This review analyzes which people have Fatigue with Methotrexate. It is created by eHealthMe based on reports of 231,270 people who have side effects when taking Methotrexate from FDA , and is updated regularly.
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On Dec, 21, 2017
231,270 people reported to have side effects when taking Methotrexate.
Among them, 9,957 people (4.31%) have Fatigue
Number of reports submitted per year:
Time on Methotrexate when people have Fatigue *:
- < 1 month: 17.92 %
- 1 - 6 months: 19.06 %
- 6 - 12 months: 11.7 %
- 1 - 2 years: 13.77 %
- 2 - 5 years: 17.55 %
- 5 - 10 years: 12.64 %
- 10+ years: 7.36 %
Gender of people who have Fatigue when taking Methotrexate *:
- female: 78.7 %
- male: 21.3 %
Age of people who have Fatigue when taking Methotrexate *:
- 0-1: 0.18 %
- 2-9: 1.3 %
- 10-19: 2.82 %
- 20-29: 2.91 %
- 30-39: 7.36 %
- 40-49: 16.28 %
- 50-59: 28.26 %
- 60+: 40.88 %
Top conditions involved for these people *:
- Psoriatic Arthropathy (820 people, 8.24%)
- Pain (626 people, 6.29%)
- High Blood Pressure (514 people, 5.16%)
- High Blood Cholesterol (333 people, 3.34%)
- Vitamin Supplementation (309 people, 3.10%)
Top co-used drugs for these people *:
- Enbrel (3,254 people, 32.68%)
- Humira (2,660 people, 26.71%)
- Folic Acid (1,836 people, 18.44%)
- Prednisone (1,079 people, 10.84%)
- Plaquenil (985 people, 9.89%)
Top other side effects for these people *:
- Pain (1,929 people, 19.37%)
- Joint Pain (1,904 people, 19.12%)
- Nausea (1,815 people, 18.23%)
- Headache (1,549 people, 15.56%)
- Weakness (1,516 people, 15.23%)
* Approximation only. Some reports may have incomplete information.
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Do you have Fatigue when taking Methotrexate?
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Expand the study to include all drugs with the same ingredientsFatigue and drugs with ingredients of methotrexate sodium.
Expand the study to include reports from both FDA and eHealthMeFatigue and Methotrexate from FDA and eHealthMe reports
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,881 users)
Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, rheumatoid arthritis, hepatitis c, high blood pressure, depression (latest reports from 406,355 Fatigue patients).
Browse all side effects of Methotrexatea b c d e f g h i j k l m n o p q r s t u v w x y z
Drugs that are associated with FatigueFatigue
Could your condition cause FatigueFatigue
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
What would happen?
Questions to the study
I have been recently given a diagnosis of rheumatoid arthritis. I had an atypical presentation with muscle pains in my thighs and later on wrist swelling. No joint pains or stiffness. Probably very early still. I am taking low dose steroids and MTX. The muscle pains improved but I developed ...
I have psoriatic arthritis and take methotrexate and plaquenil. I am doing well on these meds except for pain on the upper left side and around the back. The only relief is when I lay down. The pain is usually in the afternoon or when standing.
I HAVE RA FOR 6 YEARS STARTED COUGHING 2MONTHS AGO WENT MY PULMONARY DOCTOR. TOOK OUT PLEURAL FLUID TWICE IN 2 MONTHS. I HAVE BEEN TAKING METH0TREXATE. 25 MG 1 AWEEK FOR 6 YEARS. COULD THIS CAUSE PLEURAL FLUID AROUND LUNG; THANKS AGAIN JOHN SCALA
I was wondering if someone can help me. I have systemic candida which has been really hard to get rid of. To top it off, I take suboxone for pain. Has anyone noticed if the suboxone made the candida symptoms worse?
I have a friend taking methotrexate, folic acid, and Humira. She is taking drug test and keeps getting a positive. Someone told her it may be a "false" positive but she has to provide proof from a medical provider. Her rhematologist will not sign his name to it, being true or not. Can someone ...
User posts to the study
Hi my names Tracy I’ve been taking methotrexate for about 1year stopped part way through year,as really don’t like taking the drug but been back in it for last few months and been having heart palpitations been to doc and they don’t seem worried about it,but I am!
Hi. I’m New to the group. Am back on Gleevec after changing to Sprycel for 4 yrs and developing low O2 sats at rest and small pleural effusion. Off and on with methotrexate for Psoriasis and PsA. My hair feels like it’s getting thinner and when I wash it I’m losing quite a bit. Anyone else ...
I fell about a week ago and really scraped up my arm. However something very itchy started on my arm and nothing would fix it... I asked the pharmacist about this (as it is a weekend) and he said if I had a steroid cream I should try it... I did the ultimate wrong thing... We had some ...
Just started taking Cholestyramine about 2 weeks ago and now experiencing fatigue. Very sluggish. Never felt this way before. Male age 60 not taking any other meds at all. Just multi-vitamens & an iron pill.
Data male 38 yeas old treat with Methotrexate 2.5 mg ( from one month) dose 4 tablets /week Rheumatoid Arthritis simple case in hands fingers I have already Acne relating to the start of treating with Methotrexate 2.5 mg