Methotrexate and Skin chapped - a phase IV clinical study of FDA data

Summary:

Skin chapped is reported as a side effect among people who take Methotrexate (methotrexate sodium), especially for people who are female, 40-49 old, also take Folic Acid, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Skin chapped when taking Methotrexate. It is created by eHealthMe based on reports of 599,650 people who have side effects when taking Methotrexate from the FDA, and is updated regularly.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,312 Methotrexate users. Check the latest studies of Methotrexate.

What is Skin chapped?

Skin chapped is found to be associated with 85 drugs and 218 conditions by eHealthMe. Check the latest studies of Skin chapped.



On Jul, 15, 2026

599,650 people reported to have side effects when taking Methotrexate.
Among them, 12 people (0.0%) have Skin chapped.

Could Methotrexate cause Skin chapped?

Among these 12 people:

What is the gender of people who have Skin chapped when taking Methotrexate? *

  • female: 91.67 %
  • male: 8.33 %

What is the age of people who have Skin chapped when taking Methotrexate? *

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 10 %
  • 60+: 20 %

What are other drugs people take besides Methotrexate? *

  1. Folic Acid: 5 people, 41.67%
  2. Xanax: 3 people, 25.00%
  3. Mercaptopurine: 2 people, 16.67%
  4. Omeprazole: 2 people, 16.67%
  5. Dexamethasone: 2 people, 16.67%
  6. Enbrel: 2 people, 16.67%
  7. Hydrochlorothiazide: 2 people, 16.67%
  8. Bactrim: 2 people, 16.67%
  9. Remicade: 2 people, 16.67%
  10. Ranitidine: 2 people, 16.67%

What are other side effects people have besides Skin chapped? *

  1. High Blood Pressure: 3 people, 25.00%
  2. Rashes (redness): 3 people, 25.00%
  3. Wound Secretion: 2 people, 16.67%
  4. Lobar Pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 2 people, 16.67%
  5. Chapped Lips (cracking, fissuring, and peeling of the skin f lip): 2 people, 16.67%
  6. Cholecystitis (infection of gallbladder): 2 people, 16.67%
  7. Pleural Effusion (water on the lungs): 2 people, 16.67%
  8. Nausea And Vomiting: 2 people, 16.67%
  9. Lung Infection: 2 people, 16.67%
  10. Eating Disorder: 2 people, 16.67%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 25.00%
  2. Stress And Anxiety: 2 people, 16.67%
  3. Psoriasis (immune-mediated disease that affects the skin): 2 people, 16.67%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 16.67%
  5. Pustular Psoriasis (raised bumps on the skin that are filled with pus): 1 person, 8.33%
  6. Pain: 1 person, 8.33%
  7. Muscle Spasms (muscle contraction): 1 person, 8.33%
  8. Joint Pain: 1 person, 8.33%
  9. High Blood Cholesterol: 1 person, 8.33%
  10. Breast Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Methotrexate and have Skin chapped?

- Check whether Skin chapped is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methotrexate:

Skin chapped treatments and more:

How severe was Skin chapped and when was it recovered:

Expand to all the drugs that have ingredients of methotrexate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methotrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin chapped:

Browse all the conditions that are associated with Skin chapped:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Methotrexate) and Methotrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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