Methylene blue and Drowsiness - a phase IV clinical study of FDA data

Summary:

Drowsiness is reported as a side effect among people who take Methylene blue (methylene blue), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vasopressin, and have Depression.

The phase IV clinical study analyzes which people have Drowsiness when taking Methylene blue. It is created by eHealthMe based on reports of 1,056 people who have side effects when taking Methylene blue from the FDA, and is updated regularly.

What is Methylene blue?

Methylene blue has active ingredients of methylene blue. eHealthMe is studying from 1,064 Methylene blue users. Check the latest studies of Methylene blue.

What is Drowsiness?

Drowsiness is found to be associated with 2,864 drugs and 4,800 conditions by eHealthMe. Check the latest studies of Drowsiness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

1,056 people reported to have side effects when taking Methylene blue.
Among them, 22 people (2.08%) have Drowsiness.

Among these 22 people:

How long have people been on Methylene blue when they have Drowsiness? *

What is the gender of people who have Drowsiness when taking Methylene blue? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Drowsiness when taking Methylene blue? *

What are other drugs people take besides Methylene blue? *

What are other side effects people have besides Drowsiness? *

Hypotension (abnormally low blood pressure): 18 people, 81.82%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 12 people, 54.55%
Overdose: 10 people, 45.45%
Blood Creatine Phosphokinase Increased: 9 people, 40.91%
Body Temperature Increased: 6 people, 27.27%
Mydriasis (a dilation of the pupil): 6 people, 27.27%
Hyperkalemia (damage to or disease of the kidney): 6 people, 27.27%
Neurological Decompensation (inability of brain to maintain proper function): 6 people, 27.27%
Eye Movements - Uncontrollable: 6 people, 27.27%
Renal Impairment (severely reduced kidney function): 6 people, 27.27%

What are the existing conditions these people have? *

Depression: 13 people, 59.09%
Hypotension (abnormally low blood pressure): 8 people, 36.36%
Vasoplegia Syndrome (low systemic vascular resistance): 6 people, 27.27%
Sedation: 4 people, 18.18%
Septic Shock (shock due to blood infection): 1 person, 4.55%
Radiation Necrosis (death of cell due to radiation): 1 person, 4.55%
Pain: 1 person, 4.55%
Overdose: 1 person, 4.55%
Nausea And Vomiting: 1 person, 4.55%
Suicide Attempt: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Methylene blue and have Drowsiness?

- Check whether Drowsiness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylene blue:

Methylene blue (1,064 reports)

Drowsiness treatments and more:

Drowsiness (269,040 reports)

Browse all side effects of Methylene blue:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drowsiness:

Drowsiness (2,864 drugs)

Browse all the conditions that are associated with Drowsiness:

Drowsiness (4,800 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylene blue (the active ingredients of Methylene blue) and Methylene blue (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.