Methylin and Hypercholesterolaemia aggravated - a phase IV clinical study of FDA data

Summary:

Hypercholesterolaemia aggravated is reported as a side effect among people who take Methylin (methylphenidate hydrochloride), especially for people who are female, 60+ old, also take Xanax, and have Narcolepsy.

The phase IV clinical study analyzes which people have Hypercholesterolaemia aggravated when taking Methylin. It is created by eHealthMe based on reports of 909 people who have side effects when taking Methylin from the FDA, and is updated regularly.

What is Methylin?

Methylin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,116 Methylin users. Check the latest studies of Methylin.

What is Hypercholesterolaemia aggravated?

Hypercholesterolaemia aggravated (high levels of cholesterol in the blood) is found to be associated with 1,527 drugs and 509 conditions by eHealthMe. Check the latest studies of Hypercholesterolaemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

909 people reported to have side effects when taking Methylin.
Among them, 14 people (1.54%) have Hypercholesterolaemia aggravated.

Could Methylin cause Hypercholesterolaemia aggravated?

Among these 14 people:

What is the gender of people who have Hypercholesterolaemia aggravated when taking Methylin? *

  • female: 78.57 %
  • male: 21.43 %

What is the age of people who have Hypercholesterolaemia aggravated when taking Methylin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 36.36 %
  • 50-59: 0.0 %
  • 60+: 54.55 %

What are other drugs people take besides Methylin? *

  1. Xyrem: 7 people, 50.00%
  2. Xanax: 7 people, 50.00%
  3. Omeprazole: 6 people, 42.86%
  4. Aspirin: 5 people, 35.71%
  5. Oxybutynin: 5 people, 35.71%
  6. Gilenya: 5 people, 35.71%
  7. Niacin: 5 people, 35.71%
  8. Mirapex: 5 people, 35.71%
  9. Lovastatin: 5 people, 35.71%
  10. Coreg: 5 people, 35.71%

What are other side effects people have besides Hypercholesterolaemia aggravated? *

  1. Dyspnea (difficult or laboured breathing): 6 people, 42.86%
  2. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 6 people, 42.86%
  3. Arrhythmias (irregular heartbeat): 6 people, 42.86%
  4. Dizziness: 6 people, 42.86%
  5. White Blood Cell Count Decreased: 5 people, 35.71%
  6. Coronary Artery Stenosis (narrowing of coronary artery): 5 people, 35.71%
  7. Calcium Ionised Increased: 5 people, 35.71%
  8. Chest Pain: 5 people, 35.71%
  9. Movement - Uncoordinated: 5 people, 35.71%
  10. Lymphocyte Count Decreased: 5 people, 35.71%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 50.00%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 35.71%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 35.71%
  4. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 35.71%
  5. Menstrual Disorder (disease of menstrual cycle): 1 person, 7.14%
  6. Chest Pain: 1 person, 7.14%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
  8. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 7.14%
  9. High Blood Pressure: 1 person, 7.14%
  10. Type 2 Diabetes: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Methylin and have Hypercholesterolaemia aggravated?

- Check whether Hypercholesterolaemia aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylin:

Hypercholesterolaemia aggravated treatments and more:

How severe was Hypercholesterolaemia aggravated and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercholesterolaemia aggravated:

Browse all the conditions that are associated with Hypercholesterolaemia aggravated:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Methylin) and Methylin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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