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Methylin and Hypertension aggravated - a phase IV clinical study of FDA data

Summary:

Hypertension aggravated is reported as a side effect among people who take Methylin (methylphenidate hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Narcolepsy.

The phase IV clinical study analyzes which people have Hypertension aggravated when taking Methylin. It is created by eHealthMe based on reports of 909 people who have side effects when taking Methylin from the FDA, and is updated regularly.

What is Methylin?

Methylin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,116 Methylin users. Check the latest studies of Methylin.

What is Hypertension aggravated?

Hypertension aggravated (high blood pressure) is found to be associated with 2,746 drugs and 845 conditions by eHealthMe. Check the latest studies of Hypertension aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

909 people reported to have side effects when taking Methylin.
Among them, 47 people (5.17%) have Hypertension aggravated.

Could Methylin cause Hypertension aggravated?

Among these 47 people:

How long have people been on Methylin when they have Hypertension aggravated? *

  • < 1 month: 20 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 60 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypertension aggravated when taking Methylin? *

  • female: 64.44 %
  • male: 35.56 %

What is the age of people who have Hypertension aggravated when taking Methylin? *

  • 0-1: 0.0 %
  • 2-9: 2.78 %
  • 10-19: 5.56 %
  • 20-29: 2.78 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 19.44 %
  • 60+: 47.22 %

What are other drugs people take besides Methylin? *

  1. Ativan: 19 people, 40.43%
  2. Ritalin: 19 people, 40.43%
  3. Wellbutrin: 19 people, 40.43%
  4. Aredia: 19 people, 40.43%
  5. Zometa: 19 people, 40.43%
  6. Levaquin: 18 people, 38.30%
  7. Hydrochlorothiazide: 15 people, 31.91%
  8. Xyrem: 15 people, 31.91%
  9. Simvastatin: 15 people, 31.91%
  10. Trimox: 13 people, 27.66%

What are other side effects people have besides Hypertension aggravated? *

  1. Weight Decreased: 23 people, 48.94%
  2. Weakness: 21 people, 44.68%
  3. Nausea (feeling of having an urge to vomit): 20 people, 42.55%
  4. Back Pain: 20 people, 42.55%
  5. Pain: 20 people, 42.55%
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 19 people, 40.43%
  7. Nausea And Vomiting: 19 people, 40.43%
  8. Anaemia (lack of blood): 19 people, 40.43%
  9. Infection: 19 people, 40.43%
  10. Bone Disorder: 19 people, 40.43%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 29.79%
  2. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 13 people, 27.66%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 23.40%
  4. Multiple Myeloma (cancer of the plasma cells): 7 people, 14.89%
  5. Metastases To Bone (cancer spreads to bone): 6 people, 12.77%
  6. Drowsiness: 4 people, 8.51%
  7. Insomnia (sleeplessness): 2 people, 4.26%
  8. Depression: 2 people, 4.26%
  9. Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 2 people, 4.26%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Methylin and have Hypertension aggravated?

- Check whether Hypertension aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylin:

Hypertension aggravated treatments and more:

How severe was Hypertension aggravated and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertension aggravated:

Browse all the conditions that are associated with Hypertension aggravated:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Methylin) and Methylin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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