Zetia and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Zetia (ezetimibe), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Zetia. It is created by eHealthMe based on reports of 47,765 people who have side effects when taking Zetia from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 888 drugs and 793 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

47,765 people reported to have side effects when taking Zetia.
Among them, 75 people (0.16%) have Left ventricular dysfunction.

Could Zetia cause Left ventricular dysfunction?

Among these 75 people:

How long have people been on Zetia when they have Left ventricular dysfunction? *

What is the gender of people who have Left ventricular dysfunction when taking Zetia? *

female: 20.27 %
male: 79.73 %

What is the age of people who have Left ventricular dysfunction when taking Zetia? *

What are other drugs people take besides Zetia? *

What are other side effects people have besides Left ventricular dysfunction? *

Fatigue (feeling of tiredness): 42 people, 56.00%
Dyspnea (difficult or laboured breathing): 38 people, 50.67%
Dizziness: 35 people, 46.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 29 people, 38.67%
Stress And Anxiety: 27 people, 36.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 26 people, 34.67%
Oedema Peripheral (superficial swelling): 26 people, 34.67%
Nausea (feeling of having an urge to vomit): 26 people, 34.67%
Cardiac Murmur (an heart sound in valve abnormality): 25 people, 33.33%
Abdominal Pain: 25 people, 33.33%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 19 people, 25.33%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 18 people, 24.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 16 people, 21.33%
Cardiac Murmur (an heart sound in valve abnormality): 16 people, 21.33%
Oedema Peripheral (superficial swelling): 16 people, 21.33%
Feeling Abnormal: 14 people, 18.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.33%
Diabetes: 4 people, 5.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 4.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zetia and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zetia:

Zetia (49,113 reports)

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (888 drugs)

Browse all the conditions that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (793 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe (the active ingredients of Zetia) and Zetia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.