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Methylphenidate hydrochloride and Cystitis aggravated - a phase IV clinical study of FDA data

Summary:

Cystitis aggravated is reported as a side effect among people who take Methylphenidate hydrochloride (methylphenidate hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Cystitis aggravated when taking Methylphenidate hydrochloride. It is created by eHealthMe based on reports of 6,364 people who have side effects when taking Methylphenidate hydrochloride from the FDA, and is updated regularly.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,823 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

What is Cystitis aggravated?

Cystitis aggravated (inflammation of the wall of the bladder) is found to be associated with 2,013 drugs and 768 conditions by eHealthMe. Check the latest studies of Cystitis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

6,364 people reported to have side effects when taking Methylphenidate hydrochloride.
Among them, 51 people (0.8%) have Cystitis aggravated.

Could Methylphenidate hydrochloride cause Cystitis aggravated?

Among these 51 people:

How long have people been on Methylphenidate hydrochloride when they have Cystitis aggravated? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 50 %

What is the gender of people who have Cystitis aggravated when taking Methylphenidate hydrochloride? *

  • female: 74 %
  • male: 26 %

What is the age of people who have Cystitis aggravated when taking Methylphenidate hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.69 %
  • 30-39: 0.0 %
  • 40-49: 10.26 %
  • 50-59: 43.59 %
  • 60+: 38.46 %

What are other drugs people take besides Methylphenidate hydrochloride? *

  1. Ampyra: 11 people, 21.57%
  2. Vitamin D3: 8 people, 15.69%
  3. Fish Oil: 7 people, 13.73%
  4. Vesicare: 6 people, 11.76%
  5. Tecfidera: 5 people, 9.80%
  6. Gilenya: 5 people, 9.80%
  7. Sertraline: 5 people, 9.80%
  8. Omeprazole: 5 people, 9.80%
  9. Vitamin B12: 5 people, 9.80%
  10. Ocrevus: 5 people, 9.80%

What are other side effects people have besides Cystitis aggravated? *

  1. Fall: 12 people, 23.53%
  2. Pain In Extremity: 9 people, 17.65%
  3. Weight Decreased: 9 people, 17.65%
  4. Depression: 9 people, 17.65%
  5. Diarrhea: 9 people, 17.65%
  6. Fever: 8 people, 15.69%
  7. Stress And Anxiety: 8 people, 15.69%
  8. Drowsiness: 6 people, 11.76%
  9. Pneumonia: 6 people, 11.76%
  10. Malaise (a feeling of general discomfort or uneasiness): 6 people, 11.76%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 27 people, 52.94%
  2. Constipation: 5 people, 9.80%
  3. Muscle Spasms (muscle contraction): 4 people, 7.84%
  4. Pain: 3 people, 5.88%
  5. Sleep Disorder: 3 people, 5.88%
  6. High Blood Cholesterol: 3 people, 5.88%
  7. Depression: 3 people, 5.88%
  8. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 5.88%
  9. Nausea (feeling of having an urge to vomit): 2 people, 3.92%
  10. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 3.92%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate hydrochloride and have Cystitis aggravated?

- Check whether Cystitis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Methylphenidate hydrochloride:

Cystitis aggravated treatments and more:

How severe was Cystitis aggravated and when was it recovered:

Expand to all the drugs that have ingredients of methylphenidate hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylphenidate hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cystitis aggravated:

Browse all the conditions that are associated with Cystitis aggravated:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Methylphenidate hydrochloride) and Methylphenidate hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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