Metoclopramide and Hypoperfusion - a phase IV clinical study of FDA data

Summary:

Hypoperfusion is reported as a side effect among people who take Metoclopramide (metoclopramide hydrochloride), especially for people who are female, 60+ old, also take Lisinopril, and have Idiopathic thrombocytopenic purpura.

The phase IV clinical study analyzes which people have Hypoperfusion when taking Metoclopramide. It is created by eHealthMe based on reports of 80,804 people who have side effects when taking Metoclopramide from the FDA, and is updated regularly.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

What is Hypoperfusion?

Hypoperfusion (decreased blood flow through an organ) is found to be associated with 174 drugs and 349 conditions by eHealthMe. Check the latest studies of Hypoperfusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

80,804 people reported to have side effects when taking Metoclopramide.
Among them, 15 people (0.02%) have Hypoperfusion.

Could Metoclopramide cause Hypoperfusion?

Among these 15 people:

What is the gender of people who have Hypoperfusion when taking Metoclopramide? *

  • female: 53.33 %
  • male: 46.67 %

What is the age of people who have Hypoperfusion when taking Metoclopramide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 30.77 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 7.69 %
  • 60+: 61.54 %

What are other drugs people take besides Metoclopramide? *

  1. Lisinopril: 9 people, 60.00%
  2. Aspirin: 6 people, 40.00%
  3. Famotidine: 5 people, 33.33%
  4. Lasix: 4 people, 26.67%
  5. Temazepam: 4 people, 26.67%
  6. Acetaminophen: 3 people, 20.00%
  7. Naproxen: 3 people, 20.00%
  8. Enoxaparin Sodium: 3 people, 20.00%
  9. Bisacodyl: 3 people, 20.00%
  10. Coreg: 3 people, 20.00%

What are other side effects people have besides Hypoperfusion? *

  1. Hypotension (abnormally low blood pressure): 9 people, 60.00%
  2. Arrhythmias (irregular heartbeat): 7 people, 46.67%
  3. Heparin-Induced Thrombocytopenia: 5 people, 33.33%
  4. Acute Kidney Failure: 5 people, 33.33%
  5. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 5 people, 33.33%
  6. Hepatic Failure (liver failure): 4 people, 26.67%
  7. Back Pain: 4 people, 26.67%
  8. Dyspnea (difficult or laboured breathing): 4 people, 26.67%
  9. Multiple Drug Overdose Intentional: 4 people, 26.67%
  10. Liver Function Test Abnormal: 3 people, 20.00%

What are the existing conditions these people have? *

  1. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 13.33%
  2. Tongue Neoplasm Malignant Stage Unspecified: 1 person, 6.67%
  3. Swelling: 1 person, 6.67%
  4. Indigestion: 1 person, 6.67%
  5. Cataract (clouding of the lens inside the eye): 1 person, 6.67%
  6. Blood Pressure Abnormal: 1 person, 6.67%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
  8. Asthma: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Metoclopramide and have Hypoperfusion?

- Check whether Hypoperfusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metoclopramide:

Hypoperfusion treatments and more:

How severe was Hypoperfusion and when was it recovered:

Expand to all the drugs that have ingredients of metoclopramide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metoclopramide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoperfusion:

Browse all the conditions that are associated with Hypoperfusion:


How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Metoclopramide) and Metoclopramide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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