Metrogel and Bone pain - a phase IV clinical study of FDA data

Summary:

Bone pain is reported as a side effect among people who take Metrogel (metronidazole), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Neulasta, and have Thyroid diseases.

The phase IV clinical study analyzes which people have Bone pain when taking Metrogel. It is created by eHealthMe based on reports of 2,715 people who have side effects when taking Metrogel from the FDA, and is updated regularly.

What is Metrogel?

Metrogel has active ingredients of metronidazole. It is often used in rosacea. eHealthMe is studying from 2,819 Metrogel users. Check the latest studies of Metrogel.

What is Bone pain?

Bone pain is found to be associated with 1,812 drugs and 1,777 conditions by eHealthMe. Check the latest studies of Bone pain.

On Aug, 06, 2026

2,715 people reported to have side effects when taking Metrogel.
Among them, 21 people (0.77%) have Bone pain.

Among these 21 people:

How long have people been on Metrogel when they have Bone pain? *

What is the gender of people who have Bone pain when taking Metrogel? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Bone pain when taking Metrogel? *

What are other drugs people take besides Metrogel? *

What are other side effects people have besides Bone pain? *

Dyspnea (difficult or laboured breathing): 11 people, 52.38%
Fatigue (feeling of tiredness): 10 people, 47.62%
Anaemia (lack of blood): 10 people, 47.62%
Pleural Effusion (water on the lungs): 9 people, 42.86%
Pain: 9 people, 42.86%
Urinary Tract Infection: 8 people, 38.10%
Joint Pain: 8 people, 38.10%
Weakness: 8 people, 38.10%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 33.33%
Swallowing Difficulty: 7 people, 33.33%

What are the existing conditions these people have? *

Urticaria (rash of round, red welts on the skin that itch intensely): 6 people, 28.57%
Hypotonia (low muscle tone): 6 people, 28.57%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 28.57%
Breast Cancer: 6 people, 28.57%
Diarrhea: 6 people, 28.57%
Thyroid Diseases: 6 people, 28.57%
Fungal Infection: 5 people, 23.81%
Sinusitis (inflammation of sinus): 4 people, 19.05%
Acne (skin problems that cause pimples): 3 people, 14.29%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Metrogel and have Bone pain?

- Check whether Bone pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metrogel:

Metrogel (2,819 reports)

Bone pain treatments and more:

Bone pain (76,561 reports)

Browse all side effects of Metrogel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone pain:

Bone pain (1,812 drugs)

Browse all the conditions that are associated with Bone pain:

Bone pain (1,777 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole (the active ingredients of Metrogel) and Metrogel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.