Metronidazole and Adverse reaction - a phase IV clinical study of FDA data

Summary:

Adverse reaction is reported as a side effect among people who take Metronidazole (metronidazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Levofloxacin, and have Pneumonia.

The phase IV clinical study analyzes which people have Adverse reaction when taking Metronidazole. It is created by eHealthMe based on reports of 58,146 people who have side effects when taking Metronidazole from the FDA, and is updated regularly.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

What is Adverse reaction?

Adverse reaction is found to be associated with 653 drugs and 662 conditions by eHealthMe. Check the latest studies of Adverse reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

58,146 people reported to have side effects when taking Metronidazole.
Among them, 26 people (0.04%) have Adverse reaction.

Could Metronidazole cause Adverse reaction?

Among these 26 people:

How long have people been on Metronidazole when they have Adverse reaction? *

What is the gender of people who have Adverse reaction when taking Metronidazole? *

female: 50 %
male: 50 %

What is the age of people who have Adverse reaction when taking Metronidazole? *

What are other drugs people take besides Metronidazole? *

Levofloxacin: 9 people, 34.62%
Daptomycin: 7 people, 26.92%
Fluconazole: 7 people, 26.92%
Cefepime Hydrochloride: 5 people, 19.23%
Penicillamine: 4 people, 15.38%
Stelara: 4 people, 15.38%
Cefazolin Sodium: 4 people, 15.38%
Enbrel: 3 people, 11.54%
Methotrexate: 3 people, 11.54%
Breo Ellipta: 3 people, 11.54%

What are other side effects people have besides Adverse reaction? *

Weight Decreased: 7 people, 26.92%
Thrombocytopenia (decrease of platelets in blood): 7 people, 26.92%
Diarrhea: 7 people, 26.92%
High Blood Pressure: 6 people, 23.08%
Rashes (redness): 5 people, 19.23%
Bleeding Into The Skin: 5 people, 19.23%
Weber Tuning Fork Test Abnormal: 4 people, 15.38%
Carcinoembryonic Antigen Increased: 4 people, 15.38%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 15.38%
Hypersensitivity: 4 people, 15.38%

What are the existing conditions these people have? *

Fever: 4 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 15.38%
Pneumonia: 4 people, 15.38%
High Blood Pressure: 3 people, 11.54%
Asthma: 3 people, 11.54%
Respiratory Tract Infection Fungal: 2 people, 7.69%
Cellulitis (infection under the skin): 2 people, 7.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 7.69%
Constipation: 1 person, 3.85%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Metronidazole and have Adverse reaction?

- Check whether Adverse reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metronidazole:

Metronidazole (59,578 reports)

Adverse reaction treatments and more:

Adverse reaction (13,279 reports)

Browse all side effects of Metronidazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse reaction:

Adverse reaction (653 drugs)

Browse all the conditions that are associated with Adverse reaction:

Adverse reaction (662 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole (the active ingredients of Metronidazole) and Metronidazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.