Midazolam and Tonic clonic movements - a phase IV clinical study of FDA data

Summary:

Tonic clonic movements is reported as a side effect among people who take Midazolam (midazolam), especially for people who are female, 50-59 old, also take Diprivan, and have Anaesthesia.

The phase IV clinical study analyzes which people have Tonic clonic movements when taking Midazolam. It is created by eHealthMe based on reports of 11,245 people who have side effects when taking Midazolam from the FDA, and is updated regularly.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

What is Tonic clonic movements?

Tonic clonic movements (generalized seizure that affects the entire brain) is found to be associated with 124 drugs and 349 conditions by eHealthMe. Check the latest studies of Tonic clonic movements.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11,245 people reported to have side effects when taking Midazolam.
Among them, 18 people (0.16%) have Tonic clonic movements.

Could Midazolam cause Tonic clonic movements?

Among these 18 people:

What is the gender of people who have Tonic clonic movements when taking Midazolam? *

female: 94.44 %
male: 5.56 %

What is the age of people who have Tonic clonic movements when taking Midazolam? *

What are other drugs people take besides Midazolam? *

Diprivan: 14 people, 77.78%
Cefazolin: 6 people, 33.33%
Acetaminophen: 4 people, 22.22%
Dexamethasone: 4 people, 22.22%
Paroxetine: 4 people, 22.22%
Midazolam Hydrochloride: 3 people, 16.67%
Calcium Carbonate: 3 people, 16.67%
Chlorhexidine Gluconate: 3 people, 16.67%
Fentanyl: 3 people, 16.67%
Fluticasone Propionate: 3 people, 16.67%

What are other side effects people have besides Tonic clonic movements? *

Shock Haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 4 people, 22.22%
Pulmonary Oedema (fluid accumulation in the lungs): 4 people, 22.22%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 4 people, 22.22%
High Blood Pressure: 4 people, 22.22%
Haemorrhage (bleeding): 4 people, 22.22%
Back Pain: 4 people, 22.22%

What are the existing conditions these people have? *

Depression: 14 people, 77.78%
Anaesthesia: 14 people, 77.78%
Haemorrhage (bleeding): 12 people, 66.67%
Dry Mouth: 3 people, 16.67%
Infection: 2 people, 11.11%
Local Anaesthesia: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Midazolam and have Tonic clonic movements?

- Check whether Tonic clonic movements is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midazolam:

Midazolam (11,246 reports)

Browse all side effects of Midazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tonic clonic movements:

Tonic clonic movements (124 drugs)

Browse all the conditions that are associated with Tonic clonic movements:

Tonic clonic movements (349 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midazolam (the active ingredients of Midazolam) and Midazolam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.