Midodrine hydrochloride and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Midodrine hydrochloride (midodrine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Stroke when taking Midodrine hydrochloride. It is created by eHealthMe based on reports of 3,007 people who have side effects when taking Midodrine hydrochloride from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,275 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,311 drugs and 3,035 conditions by eHealthMe. Check the latest studies of Stroke.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

3,007 people reported to have side effects when taking Midodrine hydrochloride.
Among them, 60 people (2.0%) have Stroke.

Could Midodrine hydrochloride cause Stroke?

Among these 60 people:

How long have people been on Midodrine hydrochloride when they have Stroke? *

What is the gender of people who have Stroke when taking Midodrine hydrochloride? *

female: 39.29 %
male: 60.71 %

What is the age of people who have Stroke when taking Midodrine hydrochloride? *

What are other drugs people take besides Midodrine hydrochloride? *

What are other side effects people have besides Stroke? *

Confusional State: 22 people, 36.67%
Speech Disorder: 21 people, 35.00%
Confusion: 20 people, 33.33%
Fall: 12 people, 20.00%
Fatigue (feeling of tiredness): 10 people, 16.67%
Weakness: 8 people, 13.33%
Cough: 8 people, 13.33%
Head Injury: 8 people, 13.33%
Nausea (feeling of having an urge to vomit): 7 people, 11.67%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 10.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 23 people, 38.33%
Diarrhea: 20 people, 33.33%
Scrotal Swelling: 20 people, 33.33%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 20 people, 33.33%
Parkinson's Disease: 8 people, 13.33%
Birth Control: 5 people, 8.33%
Hereditary Angioedema (recurrent episodes of severe swelling): 4 people, 6.67%
Immune System Disorder: 4 people, 6.67%
Type 2 Diabetes: 4 people, 6.67%
Immunodeficiency Common Variable: 4 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Midodrine hydrochloride and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midodrine hydrochloride:

Midodrine hydrochloride (3,275 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Midodrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,311 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,035 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Midodrine hydrochloride) and Midodrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.