Midodrine hydrochloride and Swelling - a phase IV clinical study of FDA data

Summary:

Swelling is reported as a side effect among people who take Midodrine hydrochloride (midodrine hydrochloride), especially for people who are female, 50-59 old, also take Gabapentin, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Swelling when taking Midodrine hydrochloride. It is created by eHealthMe based on reports of 3,007 people who have side effects when taking Midodrine hydrochloride from the FDA, and is updated regularly.

What is Midodrine hydrochloride?

Midodrine hydrochloride has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 3,275 Midodrine hydrochloride users. Check the latest studies of Midodrine hydrochloride.

What is Swelling?

Swelling is found to be associated with 2,295 drugs and 2,899 conditions by eHealthMe. Check the latest studies of Swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

3,007 people reported to have side effects when taking Midodrine hydrochloride.
Among them, 43 people (1.43%) have Swelling.

Could Midodrine hydrochloride cause Swelling?

Among these 43 people:

What is the gender of people who have Swelling when taking Midodrine hydrochloride? *

female: 75.61 %
male: 24.39 %

What is the age of people who have Swelling when taking Midodrine hydrochloride? *

What are other drugs people take besides Midodrine hydrochloride? *

What are other side effects people have besides Swelling? *

Pain In Extremity: 12 people, 27.91%
Oedema (fluid collection in tissue): 11 people, 25.58%
Weakness: 10 people, 23.26%
Diarrhea: 9 people, 20.93%
Dizziness: 9 people, 20.93%
Abdominal Pain: 8 people, 18.60%
Muscle Spasms (muscle contraction): 8 people, 18.60%
Oedema Peripheral (superficial swelling): 8 people, 18.60%
Pain: 8 people, 18.60%
Muscle Aches (muscle pain): 7 people, 16.28%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 9 people, 20.93%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 11.63%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 5 people, 11.63%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 9.30%
Electrolyte Imbalance: 4 people, 9.30%
Nuclear Magnetic Resonance Imaging Abdominal: 4 people, 9.30%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.98%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.98%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 4.65%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Midodrine hydrochloride and have Swelling?

- Check whether Swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Midodrine hydrochloride:

Midodrine hydrochloride (3,275 reports)

Swelling treatments and more:

Swelling (115,742 reports)

Browse all side effects of Midodrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Swelling:

Swelling (2,295 drugs)

Browse all the conditions that are associated with Swelling:

Swelling (2,899 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on midodrine hydrochloride (the active ingredients of Midodrine hydrochloride) and Midodrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.