Minivelle and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Minivelle (estradiol), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Vitamin D3, and have Hot flush.

The phase IV clinical study analyzes which people have Weight increased when taking Minivelle. It is created by eHealthMe based on reports of 3,457 people who have side effects when taking Minivelle from the FDA, and is updated regularly.

What is Minivelle?

Minivelle has active ingredients of estradiol. eHealthMe is studying from 3,480 Minivelle users. Check the latest studies of Minivelle.

What is Weight increased?

Weight increased is found to be associated with 2,888 drugs and 3,963 conditions by eHealthMe. Check the latest studies of Weight increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

3,457 people reported to have side effects when taking Minivelle.
Among them, 83 people (2.4%) have Weight increased.

Among these 83 people:

How long have people been on Minivelle when they have Weight increased? *

What is the gender of people who have Weight increased when taking Minivelle? *

female: 100 %
male: 0.0 %

What is the age of people who have Weight increased when taking Minivelle? *

What are other drugs people take besides Minivelle? *

What are other side effects people have besides Weight increased? *

Breast Pain: 13 people, 15.66%
Fatigue (feeling of tiredness): 9 people, 10.84%
Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 10.84%
Abdominal Distension: 8 people, 9.64%
Headache (pain in head): 7 people, 8.43%
Rashes (redness): 6 people, 7.23%
Feeling Abnormal: 6 people, 7.23%
Gastritis (inflammation of stomach): 6 people, 7.23%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 6 people, 7.23%
Joint Pain: 6 people, 7.23%

What are the existing conditions these people have? *

Hot Flush (sudden feelings of heat): 29 people, 34.94%
Night Sweats (sweating in night): 15 people, 18.07%
Menopausal Symptoms: 6 people, 7.23%
Menopause (end of monthly cycles in women): 5 people, 6.02%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 5 people, 6.02%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 4.82%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 4.82%
Migraine (headache): 4 people, 4.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 3.61%
Pain: 2 people, 2.41%

* Approximation only. Some reports may have incomplete information.

Do you take Minivelle and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Minivelle:

Minivelle (3,480 reports)

Weight increased treatments and more:

Weight increased (279,371 reports)

Browse all side effects of Minivelle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,888 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Minivelle) and Minivelle (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.