Mircera and Hypertensive encephalopathy - a phase IV clinical study of FDA data

Summary:

Hypertensive encephalopathy is reported as a side effect among people who take Mircera (methoxy polyethylene glycol-epoetin beta), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Nephrogenic anaemia.

The phase IV clinical study analyzes which people have Hypertensive encephalopathy when taking Mircera. It is created by eHealthMe based on reports of 10,311 people who have side effects when taking Mircera from the FDA, and is updated regularly.

What is Mircera?

Mircera has active ingredients of methoxy polyethylene glycol-epoetin beta. eHealthMe is studying from 10,321 Mircera users. Check the latest studies of Mircera.

What is Hypertensive encephalopathy?

Hypertensive encephalopathy (neurological dysfunction induced by malignant hypertension) is found to be associated with 131 drugs and 266 conditions by eHealthMe. Check the latest studies of Hypertensive encephalopathy.

On Aug, 08, 2026

10,311 people reported to have side effects when taking Mircera.
Among them, 13 people (0.13%) have Hypertensive encephalopathy.

Could Mircera cause Hypertensive encephalopathy?

Among these 13 people:

How long have people been on Mircera when they have Hypertensive encephalopathy? *

What is the gender of people who have Hypertensive encephalopathy when taking Mircera? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Hypertensive encephalopathy when taking Mircera? *

What are other drugs people take besides Mircera? *

What are other side effects people have besides Hypertensive encephalopathy? *

Lung Infection: 4 people, 30.77%
Blood Sodium Increased: 4 people, 30.77%
Anaemia (lack of blood): 4 people, 30.77%
Hypoxic-Ischaemic Encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total): 3 people, 23.08%
Hypertensive Crisis: 3 people, 23.08%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 15.38%
Seizure Like Phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Haemoglobin Decreased: 1 person, 7.69%
Dehydration (dryness resulting from the removal of water): 1 person, 7.69%

What are the existing conditions these people have? *

Nephrogenic Anaemia (anaemia due to kidney disease): 7 people, 53.85%
High Blood Pressure: 5 people, 38.46%
Urinary Tract Infection: 4 people, 30.77%
Oedema (fluid collection in tissue): 4 people, 30.77%
Gastritis (inflammation of stomach): 4 people, 30.77%
Diabetes: 4 people, 30.77%
Constipation: 4 people, 30.77%
Cerebral Ischaemia (insufficient blood flow to the brain to meet metabolic demand): 4 people, 30.77%
Cardiac Valve Disease (heart valve disease): 4 people, 30.77%
Acidosis (build-up of carbon dioxide in the blood): 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Mircera and have Hypertensive encephalopathy?

- Check whether Hypertensive encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mircera:

Mircera (10,321 reports)

Hypertensive encephalopathy treatments and more:

Hypertensive encephalopathy (927 reports)

How severe was Hypertensive encephalopathy and when was it recovered:

Hypertensive encephalopathy in Mircera

Expand to all the drugs that have ingredients of methoxy polyethylene glycol-epoetin beta:

Hypertensive encephalopathy and drugs with ingredients of methoxy polyethylene glycol-epoetin beta (17 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mircera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertensive encephalopathy:

Hypertensive encephalopathy (131 drugs)

Browse all the conditions that are associated with Hypertensive encephalopathy:

Hypertensive encephalopathy (266 conditions)

Related publications that referenced our studies

Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on methoxy polyethylene glycol-epoetin beta (the active ingredients of Mircera) and Mircera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.