Mirena and Eosinophil count increased - a phase IV clinical study of FDA data

Summary:

Eosinophil count increased is reported as a side effect among people who take Mirena (levonorgestrel), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Lipitor, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Eosinophil count increased when taking Mirena. It is created by eHealthMe based on reports of 143,466 people who have side effects when taking Mirena from the FDA, and is updated regularly.

What is Mirena?

Mirena has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 145,266 Mirena users. Check the latest studies of Mirena.

What is Eosinophil count increased?

Eosinophil count increased is found to be associated with 769 drugs and 1,130 conditions by eHealthMe. Check the latest studies of Eosinophil count increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

143,466 people reported to have side effects when taking Mirena.
Among them, 15 people (0.01%) have Eosinophil count increased.

Could Mirena cause Eosinophil count increased?

Among these 15 people:

How long have people been on Mirena when they have Eosinophil count increased? *

What is the gender of people who have Eosinophil count increased when taking Mirena? *

female: 100 %
male: 0.0 %

What is the age of people who have Eosinophil count increased when taking Mirena? *

What are other drugs people take besides Mirena? *

What are other side effects people have besides Eosinophil count increased? *

Abdominal Pain: 8 people, 53.33%
Fatigue (feeling of tiredness): 6 people, 40.00%
White Blood Cell Count Increased: 5 people, 33.33%
Stress And Anxiety: 5 people, 33.33%
Pain In Extremity: 5 people, 33.33%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 26.67%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 4 people, 26.67%
Lymphocyte Count Decreased: 4 people, 26.67%
Hypersensitivity: 4 people, 26.67%
Headache (pain in head): 4 people, 26.67%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 26.67%
Neuralgia (pain in one or more nerves): 3 people, 20.00%
Back Pain: 2 people, 13.33%
Sinusitis Bacterial (bacterial infection of sinus): 1 person, 6.67%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 6.67%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 6.67%
Pain In Extremity: 1 person, 6.67%
Migraine (headache): 1 person, 6.67%
Hypersensitivity: 1 person, 6.67%
Cyst (a closed sac): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Mirena and have Eosinophil count increased?

- Check whether Eosinophil count increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mirena:

Mirena (145,266 reports)

Browse all side effects of Mirena:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eosinophil count increased:

Eosinophil count increased (769 drugs)

Browse all the conditions that are associated with Eosinophil count increased:

Eosinophil count increased (1,130 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel (the active ingredients of Mirena) and Mirena (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.