Mirtazapine and Myoclonic epilepsy - a phase IV clinical study of FDA data

Summary:

Myoclonic epilepsy is reported as a side effect among people who take Mirtazapine (mirtazapine), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Levetiracetam, and have Sleep disorder.

The phase IV clinical study analyzes which people have Myoclonic epilepsy when taking Mirtazapine. It is created by eHealthMe based on reports of 79,492 people who have side effects when taking Mirtazapine from the FDA, and is updated regularly.

What is Mirtazapine?

Mirtazapine has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 82,120 Mirtazapine users. Check the latest studies of Mirtazapine.

What is Myoclonic epilepsy?

Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs) is found to be associated with 154 drugs and 221 conditions by eHealthMe. Check the latest studies of Myoclonic epilepsy.



On Jul, 13, 2026

79,492 people reported to have side effects when taking Mirtazapine.
Among them, 25 people (0.03%) have Myoclonic epilepsy.

Could Mirtazapine cause Myoclonic epilepsy?

Among these 25 people:

How long have people been on Mirtazapine when they have Myoclonic epilepsy? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Myoclonic epilepsy when taking Mirtazapine? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Myoclonic epilepsy when taking Mirtazapine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 50 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 50 %

What are other drugs people take besides Mirtazapine? *

  1. Levetiracetam: 9 people, 36.00%
  2. Lacosamide: 7 people, 28.00%
  3. Perampanel: 6 people, 24.00%
  4. Valproic Acid: 5 people, 20.00%
  5. Prednisone: 1 person, 4.00%
  6. Melatonin: 1 person, 4.00%
  7. Clonazepam: 1 person, 4.00%
  8. Azathioprine: 1 person, 4.00%

What are other side effects people have besides Myoclonic epilepsy? *

  1. Drowsiness: 8 people, 32.00%
  2. Weight Increased: 7 people, 28.00%
  3. Tumor: 7 people, 28.00%
  4. Balance Disorder: 7 people, 28.00%
  5. Speech Disorder: 7 people, 28.00%
  6. Depressed Mood: 7 people, 28.00%
  7. Dyskinesia (abnormality or impairment of voluntary movement): 6 people, 24.00%
  8. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 2 people, 8.00%
  9. High Blood Pressure: 1 person, 4.00%
  10. Arrhythmias (irregular heartbeat): 1 person, 4.00%

What are the existing conditions these people have? *

  1. Sleep Disorder: 14 people, 56.00%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 24.00%
  3. Juvenile Myoclonic Epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years): 6 people, 24.00%
  4. Urinary Tract Infection: 1 person, 4.00%
  5. Hepatitis B: 1 person, 4.00%
  6. General Anaesthesia: 1 person, 4.00%
  7. Akathisia (a movement disorder characterized by a feeling of inner restlessness): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Mirtazapine and have Myoclonic epilepsy?

- Check whether Myoclonic epilepsy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mirtazapine:

Myoclonic epilepsy treatments and more:

How severe was Myoclonic epilepsy and when was it recovered:

Expand to all the drugs that have ingredients of mirtazapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mirtazapine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonic epilepsy:

Browse all the conditions that are associated with Myoclonic epilepsy:


How the study uses the data?

The study uses data from the FDA. It is based on mirtazapine (the active ingredients of Mirtazapine) and Mirtazapine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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