Misoprostol and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Misoprostol (misoprostol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Mifepristone, and have Abortion induced.

The study is created by eHealthMe based on reports of 8,111 people who have side effects when taking Misoprostol from the FDA, and is updated regularly.

What is Misoprostol?

Misoprostol has active ingredients of misoprostol. It is often used in abortion. eHealthMe is studying from 8,222 Misoprostol users. Check the latest studies of Misoprostol.

On Apr, 29, 2026

8,111 people reported to have side effects when taking Misoprostol.
Among them, 82 people (1.01%) died.

Among these 82 people:

How long have people been on Misoprostol when they died? *

What is the gender of people who died when taking Misoprostol? *

female: 77.78 %
male: 22.22 %

What is the age of people who died when taking Misoprostol? *

What are other drugs people take besides Misoprostol? *

Mifepristone: 22 people, 26.83%
Pantoprazole: 8 people, 9.76%
Furosemide: 6 people, 7.32%
Xarelto: 5 people, 6.10%
Albuterol Sulfate: 5 people, 6.10%
Diclofenac: 5 people, 6.10%
Hydroxychloroquine Sulfate: 4 people, 4.88%
Prednisone: 4 people, 4.88%
Potassium: 4 people, 4.88%
Lisinopril: 4 people, 4.88%

What are other side effects people have before they died? *

Sepsis (a severe blood infection that can lead to organ failure and death): 13 people, 15.85%
Nausea (feeling of having an urge to vomit): 12 people, 14.63%
Nausea And Vomiting: 11 people, 13.41%
Abdominal Pain: 10 people, 12.20%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 7 people, 8.54%
Abortion Induced (medically referred abortion): 6 people, 7.32%
Muscle Spasms (muscle contraction): 6 people, 7.32%
Premature Baby: 5 people, 6.10%
Fatigue (feeling of tiredness): 5 people, 6.10%
Low Birth Weight Baby: 5 people, 6.10%

What are the existing conditions these people have? *

Abortion Induced (medically referred abortion): 28 people, 34.15%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 6.10%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 5 people, 6.10%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 4.88%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 4.88%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 3.66%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 3.66%
Asthma: 3 people, 3.66%
Pain: 3 people, 3.66%
Embolism Venous (embolus may pass into the arterial system): 2 people, 2.44%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Misoprostol:

Misoprostol (8,222 reports)

Expand to all the drugs that have ingredients of misoprostol:

Death and drugs with ingredients of misoprostol (191 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Misoprostol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,141 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on misoprostol (the active ingredients of Misoprostol) and Misoprostol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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