Mitoxantrone and Mucormycosis - a phase IV clinical study of FDA data

Summary:

Mucormycosis is reported as a side effect among people who take Mitoxantrone (mitoxantrone hydrochloride), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Posaconazole, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Mucormycosis when taking Mitoxantrone. It is created by eHealthMe based on reports of 8,117 people who have side effects when taking Mitoxantrone from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Mucormycosis?

Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina) is found to be associated with 198 drugs and 691 conditions by eHealthMe. Check the latest studies of Mucormycosis.



On Aug, 04, 2026

8,117 people reported to have side effects when taking Mitoxantrone.
Among them, 56 people (0.69%) have Mucormycosis.

Could Mitoxantrone cause Mucormycosis?

Among these 56 people:

How long have people been on Mitoxantrone when they have Mucormycosis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Mucormycosis when taking Mitoxantrone? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Mucormycosis when taking Mitoxantrone? *

  • 0-1: 2.22 %
  • 2-9: 26.67 %
  • 10-19: 28.89 %
  • 20-29: 8.89 %
  • 30-39: 0.0 %
  • 40-49: 20.0 %
  • 50-59: 6.67 %
  • 60+: 6.67 %

What are other drugs people take besides Mitoxantrone? *

  1. Posaconazole: 12 people, 21.43%
  2. Cytarabine: 11 people, 19.64%
  3. Methotrexate: 7 people, 12.50%
  4. Voriconazole: 5 people, 8.93%
  5. Sorafenib: 5 people, 8.93%
  6. Micafungin: 4 people, 7.14%
  7. Dexamethasone: 4 people, 7.14%
  8. Hydrocortisone: 3 people, 5.36%
  9. Prednisolone: 3 people, 5.36%
  10. Insulin: 2 people, 3.57%

What are other side effects people have besides Mucormycosis? *

  1. Febrile Neutropenia (fever with reduced white blood cells): 14 people, 25.00%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9 people, 16.07%
  3. Fungal Infection: 8 people, 14.29%
  4. Drug Ineffective: 6 people, 10.71%
  5. Cerebral Fungal Infection (fungal infection of brain): 4 people, 7.14%
  6. Fever: 3 people, 5.36%
  7. Aplastic Anemia: 3 people, 5.36%
  8. Facial Pain: 3 people, 5.36%
  9. Pneumonia: 3 people, 5.36%
  10. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 5.36%

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 19 people, 33.93%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 25.00%
  3. B Precursor Type Acute Leukaemia (lymphoid cancer): 6 people, 10.71%
  4. Leukaemia Recurrent (repeat cancer of bone marrow or blood cells): 5 people, 8.93%
  5. Bone Marrow Conditioning Regimen: 3 people, 5.36%
  6. Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 3 people, 5.36%
  7. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 5.36%
  8. Pain: 2 people, 3.57%
  9. Immunodeficiency Disorders: 2 people, 3.57%
  10. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 2 people, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Mitoxantrone and have Mucormycosis?

- Check whether Mucormycosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mitoxantrone:

Mucormycosis treatments and more:

How severe was Mucormycosis and when was it recovered:

Expand to all the drugs that have ingredients of mitoxantrone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mitoxantrone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mucormycosis:

Browse all the conditions that are associated with Mucormycosis:


How the study uses the data?

The study uses data from the FDA. It is based on mitoxantrone hydrochloride (the active ingredients of Mitoxantrone) and Mitoxantrone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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