Monopril and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Monopril (fosinopril sodium), especially for people who are male, 60+ old, also take Lipitor, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Monopril. It is created by eHealthMe based on reports of 5,820 people who have side effects when taking Monopril from the FDA, and is updated regularly.

What is Monopril?

Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 680 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Aug, 01, 2026

5,820 people reported to have side effects when taking Monopril.
Among them, 20 people (0.34%) have Diastolic dysfunction.

Could Monopril cause Diastolic dysfunction?

Among these 20 people:

What is the gender of people who have Diastolic dysfunction when taking Monopril? *

female: 30 %
male: 70 %

What is the age of people who have Diastolic dysfunction when taking Monopril? *

What are other drugs people take besides Monopril? *

What are other side effects people have besides Diastolic dysfunction? *

Dyspnea (difficult or laboured breathing): 14 people, 70.00%
Chest Pain: 12 people, 60.00%
Headache (pain in head): 10 people, 50.00%
Tricuspid Valve Incompetence (inefficient heart valve): 10 people, 50.00%
Cardiac Failure Congestive: 10 people, 50.00%
Fatigue (feeling of tiredness): 10 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 50.00%
Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 10 people, 50.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 10 people, 50.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 45.00%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 2 people, 10.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 10.00%
Ventricular Dysfunction (heart dysfunction): 1 person, 5.00%
Upper Respiratory Tract Infection: 1 person, 5.00%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 5.00%
Diabetes: 1 person, 5.00%
Cardiomyopathy (weakening of the heart muscle): 1 person, 5.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Monopril and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Monopril:

Monopril (5,910 reports)

Browse all side effects of Monopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (680 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fosinopril sodium (the active ingredients of Monopril) and Monopril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.