Caffeine and Facial pain - a phase IV clinical study of FDA data

Summary:

Facial pain is reported as a side effect among people who take Caffeine (caffeine), especially for people who are female, 60+ old, also take Diclofenac, and have Acromegaly.

The phase IV clinical study analyzes which people have Facial pain when taking Caffeine. It is created by eHealthMe based on reports of 6,333 people who have side effects when taking Caffeine from the FDA, and is updated regularly.

What is Caffeine?

Caffeine has active ingredients of caffeine. It is often used in fatigue. eHealthMe is studying from 6,667 Caffeine users. Check the latest studies of Caffeine.

What is Facial pain?

Facial pain is found to be associated with 949 drugs and 1,435 conditions by eHealthMe. Check the latest studies of Facial pain.

On Aug, 01, 2026

6,333 people reported to have side effects when taking Caffeine.
Among them, 13 people (0.21%) have Facial pain.

Among these 13 people:

What is the gender of people who have Facial pain when taking Caffeine? *

female: 100 %
male: 0.0 %

What is the age of people who have Facial pain when taking Caffeine? *

What are other drugs people take besides Caffeine? *

What are other side effects people have besides Facial pain? *

Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 13 people, 100.00%
Pain: 13 people, 100.00%
Headache (pain in head): 13 people, 100.00%
Tooth Fracture: 13 people, 100.00%
Asthma: 13 people, 100.00%
Itching: 12 people, 92.31%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 12 people, 92.31%
Weakness: 9 people, 69.23%
Gait Disturbance: 9 people, 69.23%
Weight Loss: 8 people, 61.54%

What are the existing conditions these people have? *

Sleep Disorder: 8 people, 61.54%
Pain: 8 people, 61.54%
Muscle Aches (muscle pain): 8 people, 61.54%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 61.54%
High Blood Pressure: 8 people, 61.54%
Headache (pain in head): 8 people, 61.54%
Head Injury: 8 people, 61.54%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 8 people, 61.54%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 8 people, 61.54%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 8 people, 61.54%

* Approximation only. Some reports may have incomplete information.

Do you take Caffeine and have Facial pain?

- Check whether Facial pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Caffeine:

Caffeine (6,667 reports)

Facial pain treatments and more:

Facial pain (11,585 reports)

Browse all side effects of Caffeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facial pain:

Facial pain (949 drugs)

Browse all the conditions that are associated with Facial pain:

Facial pain (1,435 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on caffeine (the active ingredients of Caffeine) and Caffeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.