Morphine and Sle - a phase IV clinical study of FDA data

Summary:

Sle is reported as a side effect among people who take Morphine (morphine sulfate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Cimzia, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Sle when taking Morphine. It is created by eHealthMe based on reports of 180,723 people who have side effects when taking Morphine from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,911 Morphine users. Check the latest studies of Morphine.

What is Sle?

Sle (systemic lupus erythematosus) is found to be associated with 1,945 drugs and 1,614 conditions by eHealthMe. Check the latest studies of Sle.



On Aug, 22, 2025

180,723 people reported to have side effects when taking Morphine.
Among them, 533 people (0.29%) have Sle.

Could Morphine cause Sle?

Among these 533 people:

How long have people been on Morphine when they have Sle? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sle when taking Morphine? *

  • female: 96.53 %
  • male: 3.47 %

What is the age of people who have Sle when taking Morphine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.51 %
  • 20-29: 0.51 %
  • 30-39: 7.32 %
  • 40-49: 37.12 %
  • 50-59: 48.99 %
  • 60+: 5.56 %

What are other drugs people take besides Morphine? *

  1. Cimzia: 377 people, 70.73%
  2. Orencia: 373 people, 69.98%
  3. Xeljanz: 367 people, 68.86%
  4. Prednisone: 367 people, 68.86%
  5. Simponi: 359 people, 67.35%
  6. Arava: 358 people, 67.17%
  7. Folic Acid: 357 people, 66.98%
  8. Sulfasalazine: 353 people, 66.23%
  9. Remicade: 345 people, 64.73%
  10. Desoximetasone: 343 people, 64.35%

What are other side effects people have besides Sle? *

  1. Fatigue (feeling of tiredness): 390 people, 73.17%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 386 people, 72.42%
  3. Rashes (redness): 383 people, 71.86%
  4. Pericarditis (inflammation of the pericardium): 376 people, 70.54%
  5. Wound: 371 people, 69.61%
  6. Hair Loss: 371 people, 69.61%
  7. Hand Deformity: 371 people, 69.61%
  8. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 370 people, 69.42%
  9. Glossodynia (a burning or painful sensation in the tongue): 369 people, 69.23%
  10. Synovitis (inflammation of the synovial membrane): 365 people, 68.48%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 404 people, 75.80%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 260 people, 48.78%
  3. Psoriasis (immune-mediated disease that affects the skin): 234 people, 43.90%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 201 people, 37.71%
  5. Joint Pain: 197 people, 36.96%
  6. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 160 people, 30.02%
  7. Indigestion: 49 people, 9.19%
  8. Stress And Anxiety: 47 people, 8.82%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 44 people, 8.26%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 31 people, 5.82%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and have Sle?

- Check whether Sle is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Morphine:

Sle treatments and more:

  • Sle (76,933 reports)

How severe was Sle and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Morphine side effects:

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sle:

Browse all the drugs that are associated with Sle:

  • Sle (1,945 drugs)

Common conditions associated with Sle:

Browse all the conditions that are associated with Sle:

  • Sle (1,614 conditions)

Drugs similar to Morphine and Sle :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Morphine) and Morphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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