Morphine and Subdural haemorrhage - a phase IV clinical study of FDA data

Summary:

Subdural haemorrhage is reported as a side effect among people who take Morphine (morphine sulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Heparin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Subdural haemorrhage when taking Morphine. It is created by eHealthMe based on reports of 180,723 people who have side effects when taking Morphine from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Subdural haemorrhage?

Subdural haemorrhage (bleeding between the skull and the surface of the brain) is found to be associated with 297 drugs and 456 conditions by eHealthMe. Check the latest studies of Subdural haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

180,723 people reported to have side effects when taking Morphine.
Among them, 88 people (0.05%) have Subdural haemorrhage.

Could Morphine cause Subdural haemorrhage?

Among these 88 people:

How long have people been on Morphine when they have Subdural haemorrhage? *

What is the gender of people who have Subdural haemorrhage when taking Morphine? *

female: 65.31 %
male: 34.69 %

What is the age of people who have Subdural haemorrhage when taking Morphine? *

What are other drugs people take besides Morphine? *

What are other side effects people have besides Subdural haemorrhage? *

Fall: 18 people, 20.45%
High Blood Cholesterol: 9 people, 10.23%
Nausea (feeling of having an urge to vomit): 9 people, 10.23%
Insomnia (sleeplessness): 9 people, 10.23%
Headache (pain in head): 9 people, 10.23%
Fatigue (feeling of tiredness): 9 people, 10.23%
Cardiogenic Shock (inadequate circulation of blood): 8 people, 9.09%
Confusional State: 8 people, 9.09%
Rashes (redness): 8 people, 9.09%
Sinusitis (inflammation of sinus): 7 people, 7.95%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 5 people, 5.68%
Muscle Spasms (muscle contraction): 5 people, 5.68%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 5.68%
Multiple Myeloma (cancer of the plasma cells): 5 people, 5.68%
Urinary Tract Infection: 3 people, 3.41%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 3.41%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 3.41%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 3 people, 3.41%
Headache (pain in head): 2 people, 2.27%
Embolism Venous (embolus may pass into the arterial system): 2 people, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and have Subdural haemorrhage?

- Check whether Subdural haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Morphine:

Morphine (182,914 reports)

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Subdural haemorrhage:

Subdural haemorrhage (297 drugs)

Browse all the conditions that are associated with Subdural haemorrhage:

Subdural haemorrhage (456 conditions)

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Morphine) and Morphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.