Motegrity and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Motegrity (prucalopride succinate), especially for people who are male, 60+ old, also take Linzess, and have Constipation.

The phase IV clinical study analyzes which people have Hypotension when taking Motegrity. It is created by eHealthMe based on reports of 1,359 people who have side effects when taking Motegrity from the FDA, and is updated regularly.

What is Motegrity?

Motegrity has active ingredients of prucalopride succinate. eHealthMe is studying from 1,380 Motegrity users. Check the latest studies of Motegrity.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,353 drugs and 4,759 conditions by eHealthMe. Check the latest studies of Hypotension.

On Jul, 27, 2026

1,359 people reported to have side effects when taking Motegrity.
Among them, 18 people (1.32%) have Hypotension.

Among these 18 people:

What is the gender of people who have Hypotension when taking Motegrity? *

female: 50 %
male: 50 %

What is the age of people who have Hypotension when taking Motegrity? *

What are other drugs people take besides Motegrity? *

What are other side effects people have besides Hypotension? *

Fatigue (feeling of tiredness): 7 people, 38.89%
Dizziness: 5 people, 27.78%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 5 people, 27.78%
Headache (pain in head): 5 people, 27.78%
Weight Decreased: 4 people, 22.22%
Nervousness: 4 people, 22.22%
General Physical Health Deterioration (weak health status): 4 people, 22.22%
Weight Increased: 3 people, 16.67%
Infusion Related Reaction: 3 people, 16.67%
Muscle Aches (muscle pain): 3 people, 16.67%

What are the existing conditions these people have? *

Constipation: 4 people, 22.22%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 16.67%
Nausea (feeling of having an urge to vomit): 3 people, 16.67%
Asthma: 3 people, 16.67%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 3 people, 16.67%
Hereditary Angioedema (recurrent episodes of severe swelling): 2 people, 11.11%
Immune System Disorder: 2 people, 11.11%
Stress And Anxiety: 2 people, 11.11%
Organising Pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 2 people, 11.11%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Motegrity and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Motegrity:

Motegrity (1,380 reports)

Hypotension treatments and more:

Hypotension (329,856 reports)

Browse all side effects of Motegrity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Hypotension (3,353 drugs)

Browse all the conditions that are associated with Hypotension:

Hypotension (4,759 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on prucalopride succinate (the active ingredients of Motegrity) and Motegrity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.