Movicol and Orthostatic hypotension - a phase IV clinical study of FDA data

Summary:

Orthostatic hypotension is reported as a side effect among people who take Movicol (polyethylene glycol 3350), especially for people who are male, 60+ old, also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Orthostatic hypotension when taking Movicol. It is created by eHealthMe based on reports of 14,199 people who have side effects when taking Movicol from the FDA, and is updated regularly.

What is Movicol?

Movicol has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 14,249 Movicol users. Check the latest studies of Movicol.

What is Orthostatic hypotension?

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up) is found to be associated with 1,231 drugs and 1,336 conditions by eHealthMe. Check the latest studies of Orthostatic hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

14,199 people reported to have side effects when taking Movicol.
Among them, 89 people (0.63%) have Orthostatic hypotension.

Could Movicol cause Orthostatic hypotension?

Among these 89 people:

What is the gender of people who have Orthostatic hypotension when taking Movicol? *

female: 34.52 %
male: 65.48 %

What is the age of people who have Orthostatic hypotension when taking Movicol? *

What are other drugs people take besides Movicol? *

Aspirin: 15 people, 16.85%
Acetaminophen: 13 people, 14.61%
Metformin: 12 people, 13.48%
Lasix: 12 people, 13.48%
Trazodone Hydrochloride: 11 people, 12.36%
Dutasteride: 11 people, 12.36%
Ramipril: 11 people, 12.36%
Tamsulosin: 11 people, 12.36%
Augmentin: 10 people, 11.24%
Imodium: 10 people, 11.24%

What are other side effects people have besides Orthostatic hypotension? *

Fall: 19 people, 21.35%
Fainting (loss of consciousness and postural tone): 16 people, 17.98%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 14 people, 15.73%
Fever: 11 people, 12.36%
Thrombocytopenia (decrease of platelets in blood): 11 people, 12.36%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 11.24%
Anaemia (lack of blood): 10 people, 11.24%
Dizziness: 10 people, 11.24%
Diarrhea: 9 people, 10.11%
Enlarged Prostate: 8 people, 8.99%

What are the existing conditions these people have? *

High Blood Pressure: 25 people, 28.09%
Multiple Myeloma (cancer of the plasma cells): 12 people, 13.48%
Enlarged Prostate: 11 people, 12.36%
Parkinson's Disease: 9 people, 10.11%
Type 2 Diabetes: 8 people, 8.99%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 8 people, 8.99%
Pain: 7 people, 7.87%
Nausea (feeling of having an urge to vomit): 4 people, 4.49%
Cardiac Failure: 3 people, 3.37%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 3.37%

* Approximation only. Some reports may have incomplete information.

Do you take Movicol and have Orthostatic hypotension?

- Check whether Orthostatic hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Movicol:

Movicol (14,249 reports)

Browse all side effects of Movicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,231 drugs)

Browse all the conditions that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,336 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 (the active ingredients of Movicol) and Movicol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.